Hepatic abscess after liver transplantation: 1990???2000

Tachopoulou, Olympia A.; Vogt, David; Henderson, J. Michael; Baker, Mark E.; Keys, Thomas F.

doi:10.1097/00007890-200301150-00014

Cited by 58 publications

(71 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The scientific evidence in PLA in transplanted livers is limited to case reports or small series of patients. 6,7 Hepatico-jejunal anastomosis and stenosis of the bile ducts have been widely reported as risk factors for PLA. Tachopoulou et al showed that a history of hepatic artery thrombosis is a major risk factor for the development of PLA.…”

Section: Discussionmentioning

confidence: 99%

Pyogenic liver abscess: current status and predictive factors for recurrence and mortality of first episodes

Czerwonko

Huespe

Bertone

et al. 2016

HPB

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Pyogenic liver abscess: current status and predictive factors for recurrence and mortality of first episodes

Czerwonko

Huespe

Bertone

et al. 2016

HPB

View full text Add to dashboard Cite

show abstract

“…However, this is an extremely severe complication since mortality can reach 45%, essentially because of the risk of graft loss [54]. While HA can occur early after LT, the median interval to onset is 60 days (although intervals of more than 1 year have been reported) [55].…”

Section: Post-transplantation Hepatic Abscessmentioning

confidence: 99%

“…After percutaneous radiological maneuvers (biliary opacification or drainage, liver biopsy), bacteremia occurs 12 times more often in patients with a bilio-enterostomy compared with choledocho-choledochostomy [62]. In the series reported by Tachopoulou et al [55], two of 14 transplanted patients (14%) developed HA after percutaneous liver biopsy.…”

Section: Post-transplantation Hepatic Abscessmentioning

confidence: 99%

Hepatic abscess: Diagnosis and management

Lardière-Deguelte

Ragot

Amroun

et al. 2015

Journal of Visceral Surgery

186

235

View full text Add to dashboard Cite

Microbial contamination of the liver parenchyma leading to hepatic abscess (HA) can occur via the bile ducts or vessels (arterial or portal) or directly, by contiguity. Infection is usually bacterial, sometimes parasitic, or very rarely fungal. In the Western world, bacterial (pyogenic) HA is most prevalent; the mortality is high approaching 15%, due mostly to patient debilitation and persistence of the underlying cause. In South-East Asia and Africa, amebic infection is the most frequent cause. The etiologies of HA are multiple including lithiasic biliary disease (cholecystitis, cholangitis), intra-abdominal collections (appendicitis, sigmoid diverticulitis, Crohn's disease), and bile duct ischemia secondary to pancreatoduodenectomy, liver transplantation, interventional techniques (radio-frequency ablation, intra-arterial chemo-embolization), and/or liver trauma. More rarely, HA occurs in the wake of septicemia either on healthy or preexisting liver diseases (biliary cysts, hydatid cyst, cystic or necrotic metastases). The incidence of HA secondary to Klebsiella pneumoniae is increasing and can give rise to other distant septic metastases. The diagnosis of HA depends mainly on imaging (sonography and/or CT scan), with confirmation by needle aspiration for bacteriology studies. The therapeutic strategy consists of bactericidal antibiotics, adapted to the germs, sometimes in combination with percutaneous or surgical drainage, and control of the primary source. The presence of bile in the aspirate or drainage fluid attests to communication with the biliary tree and calls for biliary MRI looking for obstruction. When faced with HA, the attending physician should seek advice from a multi-specialty team including an interventional radiologist, a hepatobiliary surgeon and an infectious disease specialist. This should help to determine the origin and mechanisms responsible for the abscess, and to then propose the best appropriate treatment. The presence of chronic enteric biliary contamination (i.e., sphincterotomy, bilio-enterostomy) should be determined before performing radio-frequency ablation and/or chemo-embolization; substantial stenosis of the celiac trunk should be detected before performing pancreatoduodenectomy to help avoid iatrogenic HA.

show abstract

“…that some patients with bilomas can be successfully treated nonsurgically with percutaneous drainage and prolonged anti-infective therapy, without retransplantation [1,2,[7][8][9]. Clinical features that indicate that this conservative approach will succeed have yet to be characterized.…”

mentioning

confidence: 99%