Henoch-Schonlein syndrome in children: gastrointestinal manifestations

Glasier, Charles M.; Siegel, M J; McAlister, William H.; Shackelford, Gary D.

doi:10.2214/ajr.136.6.1081

Cited by 81 publications

(44 citation statements)

References 9 publications

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“…Spasm and ulceration are prominent. With healing, the radiographic findings revert to normal; fibrosis and stricture do not occur [2]. Our patient showed duodenal and jejunal involvement, a typical presentation that has previously been reported in a large number of patients [3].…”

Section: Discussionsupporting

confidence: 75%

CT demonstration of gastrointestinal involvement in Henoch-Schonlein syndrome

Siskind

Burrell

Pun

et al. 1985

Gastrointest Radiol

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The CT appearance of gastrointestinal involvement in Henoch-Schonlein syndrome is described. The protean manifestations of this disorder are easily confused both clinically and radiographically with those of many other conditions. Mural thickening, thickened folds, ulceration, and spasm are seen radiographically. The CT appearance of segmental mural thickening and luminal narrowing correlates well with the abnormalities seen on the small-bowel series and upper endoscopy.

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Section: Discussionsupporting

confidence: 75%

CT demonstration of gastrointestinal involvement in Henoch-Schonlein syndrome

Siskind

Burrell

Pun

et al. 1985

Gastrointest Radiol

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“…The use of steroids in HSP ramains controversial [2,7,14]. Steroids have a damaging effect on the GI tract, and peptic ulcers can be induced in children [10,12].…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal endoscopy in Henoch-Schönlein purpura

et al. 1992

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Gastrointestinal (GI) endoscopy was performed in seven patients with Henoch-Schönlein purpura (HSP). In two patients there were no cutaneous lesions at the time of endoscopy, but inflammation of the duodenum, especially of the second part, led to suspicion of the disease. Upper GI endoscopy showed abnormalities in six of seven cases, and sigmoidoscopy in one of four cases. The changes were more marked in the second part of the duodenum rather than in the bulb or the stomach. The endoscopic findings included redness, swelling, petechiae or haemorrhage, erosions and ulceration of the mucosa. Histology of the mucosal biopsy specimens revealed non-specific inflammation with positive staining for IgA in the capillaries, but failed to show vasculitis. Upper GI endoscopy, including study of IgA, can be useful in the diagnosis of HSP. Colonoscopy is less helpful, especially if limited to the sigmoid colon.

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“…Intestinal lesions consist of edematous submucous and/or hemorrhagic foci, which can affect the whole thickness of the digestive wall (Jeong et al 1997;Glasier et al 1981).…”

Section: Pathogenesis and Pathologymentioning

confidence: 99%

“…These signs point to intestinal inflammation and parietal hematoma. The lesions are found predominantly on the duodenum and the jejunum, and are mostly reversible (Glasier et al 1981;Ha et al 2000;Rha et al 2000).…”

mentioning

confidence: 99%