Henoch‐Schönlein purpura and priapism

Lind, Jolline; Mackay, A; Withers, SJ

doi:10.1046/j.1440-1754.2002.00028.x

Cited by 16 publications

(13 citation statements)

References 5 publications

(17 reference statements)

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“…In contrast, Sari et al 13 described a patient with newly diagnosed HSP presenting with priapism secondary to thrombosis of the dorsal vein of the penis, which required a penile prosthesis due to cavernosal necrosis and fibrosis. Lind et al 14 reported a case of a 9-year-old boy with newly diagnosed HSP with priapism treated successfully with caudal anaesthesia and cavernosal aspiration. These two cases are exceptions, as most patients with penile HSP have a good prognosis.…”

Section: Discussionmentioning

confidence: 99%

Unusual presentation of Henöch-Schonlein purpura

Brodie¹,

Natasha

Nitiahpapand

et al. 2018

BMJ Case Reports

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We present a rare case of a 4-year-old boy with newly diagnosed Henöch-Schonlein purpura (HSP) affecting the scrotum and penis. The patient presented to the emergency department with palpable purpura symmetrically distributed over the lower limbs. This was associated with arthritis of the right knee, abdominal pain and scrotal swelling. These symptoms were preceded by an upper respiratory tract infection (URTI). The patient was initially treated with empirical oral antibiotics for epididymitis and was discharged. He subsequently re-presented 12 days later with penile swelling, erythema and tenderness. An ultrasound scan of the penis revealed grossly oedematous subcutaneous tissue with normal penile architecture. His symptoms resolved spontaneously and the patient remains under close follow-up by the paediatric team for further sequelae of HSP.

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Section: Discussionmentioning

confidence: 99%

Unusual presentation of Henöch-Schonlein purpura

Brodie¹,

Natasha

Nitiahpapand

et al. 2018

BMJ Case Reports

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“…1 Rare cases of thrombosis involving the sagittal sinus, 2,3 tibial/fibular artery, 4 iliac/femoral vein, 5 spermatic vein, 6 and penile venous system (manifesting as priapism) 7 have been reported. 1 Rare cases of thrombosis involving the sagittal sinus, 2,3 tibial/fibular artery, 4 iliac/femoral vein, 5 spermatic vein, 6 and penile venous system (manifesting as priapism) 7 have been reported.…”

Section: Discussionmentioning

confidence: 99%

Crossing the Thrombotic Threshold

Zaidi

Berman

2014

Clin Pediatr (Phila)

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A 10-year-old male with a past medical history of attention deficit hyperactivity disorder presented with a 1-day history of acute left calf pain. Four weeks prior to admission, evanescent nonpruritic, nonerythematous nickelsize lower extremity nodules were noted following a transient nonspecific viral illness. Five days prior to development of calf pain, he was diagnosis with Henoch-Schönlein purpura (HSP) when he developed scattered nonthrombocytopenic lower extremity petechiae and mild abdominal discomfort. No specific therapy was prescribed. On the day of admission, he had been sitting stationary at a sporting event for 3 hours prior to the sudden onset of left calf pain, progressing to limp and swelling. There was no history of trauma. Family history was significant for the patient's mother experiencing 5 first trimester spontaneous abortions. She subsequently received heparin treatment during a future successful pregnancy. Further details of her evaluation were not available, although she recalled being told that she "might have a lupus anticoagulant." On arrival at the emergency department, laboratory studies where performed (Table 1), and lower extremity venous Doppler study demonstrated acute deep vein thrombosis of the left peroneal vein. Enoxaparin sodium therapy was initiated (1 mg/kg q12hr SQ) and he was admitted for further management. Petechial rash and extremity symptoms and signs readily improved over the next several days.An extensive evaluation initiated for hypercoagulability was completed. Studies are listed in Table 2.Genetic studies for factor V Leiden and prothrombin gene mutation were unremarkable; the patient was found to be doubly heterozygous for MTHFR C677T and MTHFR A1298C (with normal homocysteine level).Enoxaparin was discontinued after 3 months when a repeat Doppler study demonstrated complete resolution of thrombosis. At 2-month follow-up, factor VIII remained mildly elevated at 154%; lipoprotein A was elevated at 85.8 mg/dL. At 9-month follow-up, the child remained well. DiscussionHSP is a well-characterized, multisystem, self-limited small vessel vasculitis mainly affecting children. The

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“…We conducted a review of the published literature and found eight other patients[12345678] with HSP-associated thrombosis [Table 1]. Most patients were treated with anti-inflammatories and anticoagulants.…”

Section: Discussionmentioning

confidence: 99%

Thrombosis warning in children suffering from Henoch-Schonlein Purpura

Zhang

et al. 2013

Indian J Dermatol

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Henoch-Schonlein Purpura (HSP) is one of the most common types of vasculitis in children. The characteristic clinical manifestations include non-thrombocytopenic purpura, arthritis or arthralgia, abdominal pain, gastrointestinal hemorrhage and renal abnormalities. Thrombosis has been reported as, a rare complication of HSP. We present the case of a 14-year-old boy who was diagnosed with HSP and suspected superior mesenteric vein thrombosis. We reviewed the relevant literature and found eight similar reported cases. HSP is associated with thrombosis and HSP itself and some risk factors may result in thrombosis. We suggest that physicians should monitor patients with HSP who are at a higher risk of developing thrombosis more closely.

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Henoch‐Schönlein purpura and priapism

Cited by 16 publications

References 5 publications

Unusual presentation of Henöch-Schonlein purpura

Unusual presentation of Henöch-Schonlein purpura

Crossing the Thrombotic Threshold

Thrombosis warning in children suffering from Henoch-Schonlein Purpura

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