Hen's egg, not cow's milk, sensitization in infancy is associated with asthma: 10-year follow-up of the PIAMA birth cohort

Natural history of allergic sensitization in infants with early‐onset atopic dermatitis: results from ORCA Study

“…A recent larger birth cohort study demonstrated a strong association between food allergen sensitization, especially hen's egg and asthma development by age 6 yr (20). Our study therefore confirms that early-onset AD is often associated with sensitization to food allergens and more precisely multiple food sensitizations.…”

Early‐life sensitization to hen's egg predicts asthma and rhinoconjunctivitis at 14 years of age

“…In this study, we found that both transient early‐life sensitization and persistent early‐life sensitization to egg allergens were associated with asthma and RC at 14 years (aOR = 5.52, aOR = 4.46 and aOR = 5.44, aOR = 6.06). The same conclusion of sensitization to egg allergens at 1 year and subsequent allergic asthma at 8 years was made in the Dutch PIAMA study . In the MACS study, no association between monosensitization to milk or egg at age 1 year and wheeze at 12 years of age was found.…”

“…The same conclusion of sensitization to egg allergens at 1 year and subsequent allergic asthma at 8 years was made in the Dutch PIAMA study. 17 In the MACS study, 18 no association between monosensitization to milk or egg at age 1 year and wheeze at 12 years of age was found. These two studies were enriched with atopy highrisk children and thus did not represent the general population.…”

Native and denatured egg white protein IgE tests discriminate hen's egg allergic from egg‐tolerant children

“…Egg white sensitization per se is also know to be associated with an increased risk of developing further respiratory allergies and asthma and a high percentage of children suffering with atopic dermatitis are sensitized to egg white, while most of them are tolerant to eggs . Increasing evidences show that delayed introduction of foods in infants can led to an increased risk of atopic dermatitis , food allergies , celiac disease , and respiratory allergies .…”