Hemostatic embolization of renal artery pseudoaneurysm using absorbable surgical suture (FairEmbo concept)

Diop, Abdoulaye Dione; Diop, Abdoulaye Ndoye; Hak, Jean-François; Bisceglie, Mathieu Di; Bartoli, Jean-Michel; Guillet, Benjamin; Vidal, Vincent

doi:10.1016/j.diii.2020.04.002

Cited by 8 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The feasibility of using suture fragments has been demonstrated in previous preclinical studies and through a clinical case reported in 2020 [ 10 , 11 , 12 ]. This study demonstrated the feasibility and efficacy of suture embolization through a new and previously untested application: uterine artery embolization in a female porcine model in which the uterine arteries were stimulated by gonadotropin hormone administration.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

FairEmbo Concept for Postpartum Hemorrhage: Evaluation of the Efficacy of Suture Fragment Compared with Gelatin Sponge Torpedo Embolization in a Post-Gravid Swine Model

Gang-Ny

Panneau

Brige

et al. 2023

JPM

View full text Add to dashboard Cite

Background: Postpartum hemorrhage is the leading cause of maternal mortality in emerging countries. This study aims to evaluate the effectiveness and safety of uterine artery embolization (UAE) using suture fragment (FairEmbo concept) in a swine model. Methods: Seven female swine uteri were embolized. The left uterine artery was embolized with 1 cm fragments of absorbable suture (Optime® 0), and with gelatin sponge torpedoes for the contralateral side for comparison. The embolization effectiveness and the time for arterial recanalization with digital subtraction angiography (DSA) controls at D0, D7, and M1, were evaluated. Follow-up protocol also included clinical monitoring and macroscopical analyses at M1. A Mann–Whitney test (significance at P 0.05) was used for statistics. Results: A technical success was obtained for the seven arteries on each side, with no off-target embolization. The procedure time (10 min versus 3.7 min) and number of fragments (13.8 versus 5.7) required for complete occlusion were significantly greater in the FairEmbo group. All arteries were repermeabilized at M1. No necrosis was macroscopically visible at harvest at M1. Conclusion: This experimental study suggests that UAE with SBM FairEmbo method is feasible, safe, and effective in comparison with gelatin sponge procedure.

show abstract

Section: Discussionmentioning

confidence: 99%

“…It has recently demonstrated that embolization with suture fragments is feasible and effective in short- and medium-term follow-up in porcine models [ 10 , 11 ]. Its clinical efficacy was also demonstrated by clinical case emergency embolization of a renal artery pseudoaneurysm in 2020 [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

FairEmbo Concept for Postpartum Hemorrhage: Evaluation of the Efficacy of Suture Fragment Compared with Gelatin Sponge Torpedo Embolization in a Post-Gravid Swine Model

Gang-Ny

Panneau

Brige

et al. 2023

JPM

View full text Add to dashboard Cite

show abstract

“…The first FairEmbo study reported the feasibility, effectiveness and safety for proximal embolization using homemade and extemporaneously torpedo-form embolic agents from absorbable and non-absorbable suture fragments of 1 to 2 cm [7]. This was confirmed by a recent clinical case report, showing effective hemostatic embolization of a renal artery pseudoaneurysm using absorbable torpedo-form suture fragment [8].…”

Section: Introductionmentioning

confidence: 90%

FairEmbo Concept for Arterial Embolizations: In Vivo Feasibility and Safety Study with Suture-Based Microparticles Compared with Microspheres

Bisceglie

Hak

Diop

et al. 2020

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

Purpose: Microspheres are effective embolic agents especially for the management of bleeding and oncologic lesions. The first FairEmbo study reported the effectiveness of embolization using suture fragments. The effectiveness and safety of arterial embolization with Suture-Based Microparticles (SBM) were assessed in a swine model. Materials and methods:In this ethical-approved animal study, a polar artery in each kidney was embolized in four swine: one side with hand-cut non-absorbable SBM (Flexocrin 2 ® ) and the contralateral side with Embozene ® 900 for comparison. Swine were followed for 3 months (M3) to evaluate the effectiveness and the safety of SBM.Follow-up protocol included clinical monitoring, computed tomography (CT) control and digital subtraction angiography (DSA), followed by histological analyses. The SBM confection parameters were evaluated by automatic microscopic sizer. RStudio software and Mann-Whitney test (significance at P<0.05) were used for statistics. Results:The average size of SBM was 1002μm (SD=258). All targets were effectively embolized by SBM, with an angiogram defect estimated at 45.6% (95% CI [35.9-55.2]), compared to 40.5% (95% CI [30.6-55.5]) for Embozene ® group, without significant difference (P=0.342). The average duration of SBM embolization procedure was significantly increased compared to Embozene ® embolization (1202s versus 222s, P=0.029). There were no statistical differences in M3 DSA and CT for SBM and Embozene ® , with persistence of partial arterial occlusion and atrophic embolized area. No postoperative complications were observed on clinical and CT controls. Conclusion:This experimental study suggests that embolization with SBM is safe and effective in short and medium-term follow-up as compared to microspheres.

show abstract

“…The paper, ''FairEmbo concept for arterial embolizations: In vivo feasibility and safety with suture-based microparticles compared with microspheres'' introduced the technique of ''cutting the thread into small pieces'' and showed the possibility that this technique can reduce the cost of IR [3]. In the current trend where most interventional radiologists hope to use expensive and high quality imaging equipment and devices, the attitude of conducting research and publishing papers from the viewpoint of ''cheaper IR'' is commendable [4,5]. We should also not forget that by using good technique, we may be able to accomplish similar quality IR with cheaper imaging equipment.…”

mentioning

confidence: 99%

Interventional Radiology for Whom

Arai

2021

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

Hemostatic embolization of renal artery pseudoaneurysm using absorbable surgical suture (FairEmbo concept)

Cited by 8 publications

References 4 publications

FairEmbo Concept for Postpartum Hemorrhage: Evaluation of the Efficacy of Suture Fragment Compared with Gelatin Sponge Torpedo Embolization in a Post-Gravid Swine Model

FairEmbo Concept for Postpartum Hemorrhage: Evaluation of the Efficacy of Suture Fragment Compared with Gelatin Sponge Torpedo Embolization in a Post-Gravid Swine Model

FairEmbo Concept for Arterial Embolizations: In Vivo Feasibility and Safety Study with Suture-Based Microparticles Compared with Microspheres

Interventional Radiology for Whom

Contact Info

Product

Resources

About