Hemostasis in renal failure

Boccardo, Paola

doi:10.1007/s003900050164

Cited by 1 publication

(1 citation statement)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Meskipun dapat mengurangi komplikasi perdarahan yang berhubungan dengan uremia, resiko tersebut tidak dapat sepenuhnya dieliminasi. 5,13,21,22 Resiko perdarahan akibat heparin dapat diminimalkan dengan beberapa cara, pertama, heparinisasi regional atau antikoagulan sitrat regional. Untuk tehnik heparinisasi regional, heparin diinfus menuju peralatan dialisa dan protamin sebagai antiheparin dimasukkan setelah darah keluar dari peralatan dialisa.…”

Section: Peran Dialisisunclassified

Gangguan Hemostasis Pada Penyakit Ginjal Kronik Derajat 5

Pramana

2022

JKU

View full text Add to dashboard Cite

Patients with chronic kidney disease (CKD) develop hemostatic disorders mainly in the form of bleeding diatheses. Platelet dysfunction is the main factor responsible for hemorrhagic tendencies in advanced kidney disease. Anemia, dialysis, the accumulation of medications due to poor clearance, and anticoagulation used during dialysis have some role in causing impaired hemostasis in CKD patients. Platelet dysfunction occurs both as a result of intrinsic platelet abnormalities and impaired platelet-vessel wall interaction. The normal platelet response to vessel wall injury with platelet activation, recruitment, adhesion, and aggregation is defective in advanced renal failure. Dialysis may partially correct these defects, but cannot totally eliminate them. The hemodialysis process itself may in fact contribute to bleeding. Hemodialysis is also associated with thrombosis as a result of chronic platelet activation due to contact with artificial surfaces during dialysis.

show abstract

Section: Peran Dialisisunclassified

Gangguan Hemostasis Pada Penyakit Ginjal Kronik Derajat 5

Pramana

2022

JKU

View full text Add to dashboard Cite

show abstract

Hemostasis in renal failure

Cited by 1 publication

References 74 publications

Gangguan Hemostasis Pada Penyakit Ginjal Kronik Derajat 5

Gangguan Hemostasis Pada Penyakit Ginjal Kronik Derajat 5

Contact Info

Product

Resources

About