Hemostasis and complement in allogeneic hematopoietic stem cell transplantation: clinical significance of two interactive systems
Dimitrios A. Tsakiris,
Eleni Gavriilaki,
Ioanna Chanou
et al.
Abstract:Hematopoietic stem cell transplantation (HCT) represents a curative treatment option for certain malignant and nonmalignant hematological diseases. Conditioning regimens before HCT, the development of graft-versus-host disease (GVHD) in the allogeneic setting, and delayed immune reconstitution contribute to early and late complications by inducing tissue damage or humoral alterations. Hemostasis and/or the complement system are biological regulatory defense systems involving humoral and cellular reactions and … Show more
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