Hemorrhagic fever with renal syndrome (HFRS) in Poland

Abstract

Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis occurring due to the hantavirus infection. On the territory it constitutes the only case of viral hemorrhagic fever. The infections occurring in Poland are mainly caused by the Puumala and Dobrava serotypes. The pathogenetic influence of other Hanta serotypes such as Boginia, Nova and Seewis on humans is still unknown. The endemic territory of the occurrence of the hantavirus infections in Poland is the Podkarpacie region. The morbidity is not high and ranges between 0.02 and 0.14 in every 100 000 but professional literature suggests that the data concerning the territory of Poland is underestimated. So far hantavirus infections have not been reported in other areas of Poland yet the presence of the virus may be excluded. In view of literature and the significant occurrence of Hanta antibodies in patients included in the risk group, it may be claimed that the diseases caused by Hanta virus constitute a significant factor influencing the medical status of the group in focus all over the country.

Vaccines and Therapeutics Against Hantaviruses

“…Outside North America, individual cases and small clusters of HCPS have been reported in Balkans, northern Sweden (Bergstedt Oscarsson et al, 2016), Argentina (Pini et al, 2003), Chile (Toro et al, 1998), Poland (Gut et al, 2018), Bolivia (1998), Brazil (Suzuki et al, 2004;Limongi et al, 2009), Serbia (Stanojevic et al, 2019), United Kingdom (Duggan, 2019), Panama (Bayard et al, 2004), and Germany (Ettinger et al, 2012). Overall, in Europe, the incidence of hantavirus infections has steadily increased in recent years: In 2014, a record number of 3754 infections were registered across Europe .…”

“…In Poland, the infections are caused by mainly the PUUV and DOBV serotypes. The morbidity is not high; it ranges between 0.02 and 0.14 per 100,000 cases, but some papers suggest that the data concerning Poland is underestimated (Gut et al, 2018), because the number of infections then was higher, and it was most likely the epidemic year. In the following year, 2015, there were 6 infections, and in 2016 and 2017, there were 8 and 14 cases registered, respectively.…”

TBE In Poland

“…This was the catalyst for scientific research studies by Przesmycki's team in selected regions of the country in the years 1953 through 1957. 2 In these studies, tick-borne encephalitis viruses (TBEV) were isolated from human specimens as well as from animal samples (small mammals) and vectors (ticks). Isolated viruses were determined to be TBEV, European sub-type.…”

“…Isolated viruses were determined to be TBEV, European sub-type. [2][3][4] Seroprevalence studies were conducted in the late 1960s and early 1970s. Serum samples collected from ~17,000 blood donors and 20,000 forest workers living in different parts of Poland were examined.…”

“…These seroprevalence data also indicated high numbers of asymptomatic or non-severe infections among the tested populations. 2,[5][6][7][8][9] A distribution map of TBE cases and confirmed presence of TBEV in Poland was developed, based on results from seroprevalence studies, virus isolation and clinical data. Some regions were determined to be endemic for TBEV.…”