Hemorrhagic corpus luteum: Clinical management update

Медведєв, М. В.; Malvasi, Antonio; Gustapane, Sarah; Tinelli, Andrea

doi:10.4274/tjod.galenos.2020.40359

Cited by 19 publications

(32 citation statements)

References 54 publications

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“…In this case, we first suspected ovarian hemorrhage because the patient was on cycle date 12 at the time of first visit and stated that she had sexual intercourse before development of symptoms. However, large ascites (intraperitoneal hemorrhage), which is often seen in ovarian hemorrhage [ 10 ], was not observed at this time. When a sudden abdominal pain occurs in a young woman and there remains some unclear findings, otherwise-normal ovarian torsion should be included in the differential diagnosis, and careful follow-up is recommended.…”

Section: Discussionmentioning

confidence: 95%

A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis

Yamanoi

Sunada

et al. 2021

Case Reports in Obstetrics and Gynecology

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We report a case of torsion in an otherwise-normal ovary with a giant hematosalpinx. A 23-year-old woman presented with complaints of abdominal pain and nausea. At initial visit, there was few abnormal findings of imaging tests, and we made a diagnosis of ovarian hemorrhage. Three days later, she came back with increased symptoms, and we detected the mass of a complex solid cystic structure with a unilocular cyst much larger than solid component. A diagnostic laparoscopy was performed immediately, and we could make a diagnosis of torsion in an otherwise-normal ovary with a giant hematosalpinx. We performed a salpingectomy and could preserve her ovary. This is the first case of torsion in an otherwise-normal ovary with a giant hematosalpinx which enlarged to a greater extent than the ovary.

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Section: Discussionmentioning

confidence: 95%

A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis

Yamanoi

Sunada

et al. 2021

Case Reports in Obstetrics and Gynecology

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“…Complete coagulation screening is essential for the identification of patients with bleeding disorders, anamnesis, anticoagulant therapy. In addition, family history can also provide important information [ 1 ]. Phenotype evaluation and molecular diagnosis will help a lot to distinguish different kinds of coagulative disorders [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

“…Recurrent episodes occurred in 2 of the patients with certain congenital bleeding disorders and conservative management with blood product and factor concentrate support was successful in avoiding surgery in 3 of the 5 episodes of bleeding [ 2 ]. The observational approach in hemodynamically stable patients could be the first-choice option in most cases [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…Conservative management like antifibrinolytic, liquid infusion, blood transfusions and antibiotic would be selected since the hemorrhagic CL is often self-limiting. Laparoscopy is preferred rather than laparotomy in most operative managements, with surgical options such as luteumectomy, ovarian wedge-shaped excision or oophorectomy [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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Corpus luteum hemorrhage with acquired hemophilia A: a case report and literature review

Xie¹,

Jiang²

2022

BMC Women's Health

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Background The rupture of the corpus luteum (CL) may occur at all stages of a woman’s reproductive life. Bleeding of the ruptured CL varies from self-limiting hemorrhage to massive hemoperitoneum, causing the shock and subsequent emergency surgery. But hemoperitoneum secondary to ruptured CL is a rare complication and situation for women with bleeding disorders. Case presentation We here describe a case of severe CL hemorrhage with factor VIII deficiency. We chose conservative management instead of surgery for the abnormal hemostatic condition. With blood product and factor concentrate support, conservative management was successful in avoiding surgery in the episode of bleeding. Conclusion Gynecologist should be alert for the patients with abnormal hemostatic condition. Selective patients presenting with CL hemoperitoneum association with bleeding disorders may undergo conservative management and avoid the risk of surgery.

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“…Hemorrhagic ovarian cysts may result from bleeding into the residual follicle at the time of ovulation, which potentially leads to intraperitoneal bleeding and the need for surgical intervention. 3,10,28,29 Endometriosis, a chronic condition affecting 5 to 10% of women of reproductive age in which endometrial tissue is present outside of the uterus, was more likely to be detected in women with VWD. 28,30,31 Clinically, endometriosis is associated with severe cyclic pain, dysmenorrhea, dyspareunia, and dysuria and can Table 2 Recommendation on obstetric management in VWD; adapted from Connell et al 19…”

Section: Heavy Menstrual Bleeding and Other Reproductive Conditionsmentioning

confidence: 99%

Von Willebrand Disease—Specific Aspects in Women

Eladly

Miesbach

2022

Hamostaseologie

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Von Willebrand disease (VWD) is the most common inherited bleeding disorder, which results from a deficiency or dysfunction of von Willebrand factor (VWF). The major symptoms of patients affected by VWD include mucocutaneous and gastrointestinal bleeding, easy bruising, and prolonged provoked bleeding due to injury or surgery. Although women and men are equally likely to be affected by VWD, women continue to be disproportionately affected by the bleeding challenges. Women with VWD suffer from sex-specific symptoms, such as menorrhagia, and are at higher risk of reproductive problems and recurrent miscarriage. Furthermore, pregnant women with VWD are more likely at higher risk of suffering from primary and secondary peripartal hemorrhage and anemia and the need for transfusions. Despite being affected by gynecologic and obstetrical bleeding, women face multiple barriers in obtaining an accurate diagnosis. This constitutes a problem that needs to be addressed, and early appropriate medical care should be ensured. There are several effective treatment options for women with VWD that can significantly improve their quality of life, including desmopressin, VWF concentrates, hormonal therapy, and antifibrinolytic therapy. During pregnancy, the monitoring of VWF activity levels is essential. The peripartal management depends on the type of VWD and on the measured levels of VWF levels and activity prior to delivery.

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Hemorrhagic corpus luteum: Clinical management update

Cited by 19 publications

References 54 publications

A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis

A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis

Corpus luteum hemorrhage with acquired hemophilia A: a case report and literature review

Von Willebrand Disease—Specific Aspects in Women

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