Hemorrhagic brain metastasis from osteogenic sarcoma of iliac bone in young female: Unusual site of presentation

Dwivedi, Amit Nandan Dhar; Gupta, Prashant; Gupta, Kumkum; Garg, Gouri

doi:10.4103/0028-3886.84361

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…14 15 Due to its higher vascularity, these lesions can mimic other tumors like glioblastoma 17 and higher association with intratumoral bleeding. 18 Brain metastasis in sarcoma is relatively rare and approximately only 3% of all brain metastases can develop from sarcomas according to the few studies. 16 19 Postulated mechanisms are hematogenous dissemination into the brain as the primary cause and contiguous extension from the skull bone to the brain as the secondary cause.…”

Section: Discussionmentioning

confidence: 99%

Isolated Cerebral Metachronous Metastasis in Fibular Osteosarcoma: A Rare Case Report with Review of Literature

Nayak,

Rastogi,

Sebastian

et al. 2023

Indian J Med Paediatr Oncol

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Isolated brain involvement is rarely reported as isolated metachronous metastasis from osteosarcoma. Herein, we report a case of fibular osteosarcoma in a young female who presented with solitary hemorrhagic metachronous cerebral metastasis after years of disease-free interval. Imaging showed a large mass lesion in the right posterior temporal lobe with internal areas of bleed not associated with calcification or ossification mimicking high-grade glioma. No other sites of distant metastases were found on the workup. Two-dimensional echocardiography was done to rule out any cardiac anomaly, including the shunt defect, but no abnormality was detected. She was operated for the cerebral lesion, and histopathology of the resected specimen showed osteosarcoma. The patient was started on chemotherapy and is doing well so far. This case presents a unique scenario of osteosarcoma with an isolated lesion in the brain without any other site of distant metastasis.

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