Pancreaticoduodenectomy (PD) performed for benign and malignant conditions can be complicated by delayed gastric emptying, anastomotic leaks, and postoperative pancreatic fistula, leading to significant morbidity. 1 Though less common, postpancreatectomy hemorrhage (PPH) may occur in up to 16% of patients with an associated mortality nearing 40%. 2 In this issue of JAMA Surgery, Preston et al 3 present a large contemporary study on rates, etiology, and management of PPH from 2 high-volume pancreatic centers. Although 3% of the more than 3000 patients included had a PPH, only 16.7% were due to bleeding from the gastroduodenal artery (GDA). It is common practice to address the GDA with embolization or stent during interventional radiology procedures. When an alternate or unidentified PPH source was identified, 13.7% and 58.3% of patients, respectively, underwent empirical GDA treatment. Despite similar 90-day mortality between patients receiving or not receiving GDA embolization/stent (15.0% vs 10.0%, P = .52), 20% experienced biliary stricture or hepatic infarct. Unfortunately, these complications were associated with a significant increase in 90-day mortality (38.5% vs 7.8% in those without complication, P = .008).Although a small number of patients had PPH in this study, the conclusions are significant because they relate to the management of the GDA in the face of PPH. It is unlikely