Hemorrhage, Phenobarbital, and Fluctuating Cerebral Blood Flow

Abstract

In the recent article regarding fluctuating cerebral blood flow velocity and the intraventricular hemorrhage in the neonate, the authors concluded "when the best 20 waves are chosen to evaluate the coefficient of variation, no association exists between the coefficient of variation values and development of subependymal-intraventricular hemorrhage...." Such a conclusion is clearly not justified based on the data presented. First, the mean mode as was used in this study is an averaged frequency for a single cycle.