Hemorrhage from a cavernous hemangioma with fatal blood aspiration: A rare cause of sudden unexpected death

Multiple Cavernous Hemangiomas of the Lung

“…This leads to high waiting list mortality for lung transplant recipients. Ex vivo lung perfusion (EVLP) is a novel technique proposed for the assessment, resuscitation, and repair of extended donor lungs [1,2]. Similar early outcomes have been reported in recipients who underwent transplantation after EVLP to those with conventionally selected and transplanted lungs [1][2][3].…”

“…In the case reported here, PCHs invaded the large airway. If the lesions break through the mucous layer, there will be hemoptysis, even leading to lethal blood aspiration [1]. In general, PCHs seldom regress, nor do they rapidly progress.…”

“…The lung was accepted for EVLP and reconditioning during EVLP with urokinase. Acellular normothermic EVLP [1] was performed.…”

“…They can affect any visceral organ but rarely occur in the lung. According to a review of the international literature, only 10 cases of pulmonary cavernous hemangiomas (PCHs) were reported during the 60 years before 2010 [1]. We describe a patient with multiple PCHs verified by lung biopsy.…”

Multiple cavernous hemangiomas of the lung and liver mimicking metastasis

“…[2] According to a previous review of the international literature, only 10 cases of pulmonary cavernous hemangiomas (PCHs) were reported during the 60 years prior to 2010. [3] Some literature reported cavernous hemangiomas not only occurring in the lung, but also appearing in other organs of the body, such as the liver and pericardium. [2,4,5] Severe bleeding caused by rupture of HCHs has been reported which leads to death.…”