Hemorragia gastrointestinal de origen oscuro por tumores de estroma gastrointestinal

Abstract

GIST can have multiple clinical pictures and unusual symptoms, such as obscure gastrointestinal bleeding. The use of computed tomography and angiography has shown to be an important tool in the diagnosis with patients with small intestine GISTs.

Surgical treatment of giant gist with acute gastrointestinal bleeding: Case report

“…Approximately 95% of GISTs are positive for CD117 [ 1 ]. The most importante prognostic factors related to these tumors are the mitotic índex, size and location [ 2 , 11 ].…”

“…The cause of their hemorrhagic potential is the ulceration of the mucosa [ 11 ]. The tumors of small bowel are responsible for 5–10% of occult digestive tract haemorrhage [ 2 ]. An abdominal mass may be noticeable with tumoral growth.…”

“…An abdominal mass may be noticeable with tumoral growth. Most patients with GISTs present variable clinical presentation, which also depends on the size and location of the tumor [ 1 , 2 ]. The median size of GISTs at diagnosis is 5–7 cm, although these tumors may grow over 30 cm.…”

“…Surgical resection is the basis of treatment of GISTs and treatment with Imatinib, a tyrosine kinase inhibitor, is beneficial after resection surgery of high-risk GISTs [ 2 , 4 , 5 , 9 , 12 ]. In the case presented, the patient was submitted to radical surgical resection and then started Imatinib therapy, with a result of a follow-up period of 3 years without evidence of disease recurrence.…”

“…Gastrointestinal stromal tumors (GISTs) are considered rare tumors. However, they are the most common mesenchymal neoplasms of the gastrointestinal tract [ 1 , 2 , 7 ]. The small intestine is the second-most frequent location where GISTs may occur, after the stomach.…”