Hemorajik Ve İskemik Serebrovasküler Hastalık Tanısı Alan Hastalarda Kan Laktat Düzeyinin Prognoz Üzerine Etkisi

Çağlayan, Turgay; Özakın, Engin; Özdemi̇r, Atilla Özcan; Acar, Nurdan; Çanakçı, Mustafa Emin; Arslan, Ebubekir; Dolgun, Hakan

doi:10.20515/otd.796303

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…In another study, venous blood lactate levels over 2 mmol/L were shown to have a positive correlation with increased 3‐month mortality rates 13 . Yet another study on the effect of blood lactate level on the prognosis of stroke patients showed no correlation for ischemic stroke prognosis but a significantly positive correlation in haemorrhagic stroke prognosis 25 .…”

Section: Discussionmentioning

confidence: 97%

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Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short‐ and long‐term mortality risk

Sakal

Taşçı

et al. 2021

Int J Clin Pract

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Objective: Our study was carried out on patients admitted to the emergency ward with acute stroke symptoms that were subsequently diagnosed with cerebrovascular disease. We aimed to examine the relationship between these patients' admission lactate levels and their 1-, 3-, and 12-month mortality rates in order to evaluate the prognostic value of lactate levels.Methods: Our data were obtained retrospectively from 568 patients diagnosed with acute ischemic stroke at our emergency department between 1 January 2017 and 1 January 2018. Patient data were accessed via the hospital patient database. Included patients' files were assessed for examination and history taken at admission, comorbid diseases, demographic characteristics, treatments utilized, and laboratory results.Hyperlactatemia was defined as a lactate level of over 2 mmol/L. The relationship between lactate levels and survival was investigated. Patients' complication rates after discharge were assessed alongside their 1-, 3-, and 12-month mortality.Results: Our study assessed 568 patients. Out of these patients, 400 patients met our inclusion criteria and constituted the study population. These patients were separated into two groups according to their lactate levels. The hyperlactatemic group had a statistically significant increase in 1-, 3-, and 12-month mortality rates in comparison to the other group. Conclusions:Our study found that hyperlactatemia was associated with a higher risk of 1-, 3-, and 12-month mortality, suggesting that it has predictive prognostic value.In the future, we believe that prospective observational studies and/or large-scale retrospective studies will be of great value in providing more insight into this topic. What's known• In previous studies carried out using magnetic resonance spectroscopy and microdialysis, lactate appeared to accumulate at the site of lesions in ischemic stroke patients.

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Section: Discussionmentioning

confidence: 97%

“…Rapid advances in the treatment of cerebrovascular diseases have resulted in their shift from the third to the fourth most common cause of death in the United States of America 2,3 . Events related to cerebrovascular diseases represent 25.2% of all deaths in Turkey, making them the second most common cause of death 4 .…”

Section: Introductionmentioning

confidence: 99%

Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short‐ and long‐term mortality risk

Sakal

Taşçı

et al. 2021

Int J Clin Pract

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A Parameter Affecting the Pre-Hospital Approach: Capillary Lactate Measurement

KARTAL GÜNEN

2023

Hastane Öncesi Dergisi

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Laktat, genellikle anaerobik metabolizmanın yan ürünü olarak hipoperfüzyon durumlarında yükselen ve doku hipoksisini belirlemede kullanılan önemli bir parametredir. Günümüzde sağlık hizmeti veren kurumlarda özellikle de acil servislerde hastalardaki laktat düzeyinin belirlenmesi büyük önem taşımaktadır. Çünkü laktat seviyesindeki artış mortalite ve morbidite hakkında bilgi vermekte bu nedenle hastalara olan acil yaklaşımı önemli ölçüde etkilemektedir. Laktat seviyesi ölçümü hastane ortamında venöz veya arteriyel yapılmaktadır. Son yıllarda ise laktat seviyesini ölçmek basit ve hızlı bir hale gelmiştir. Portatif cihazlar ile parmak ucu kapiller laktat ölçümü yapılabilmektedir. Özel beceri gerektirmeden hastane öncesinde de laktat değerini belirlemeye olanak sağlayan portatif kompakt laktat analizörleri geliştirilmiştir. Bu analizörlerin hastane öncesi kritik durumdaki hastaların hızlı tespit edilmesine ve sağlık profesyonellerine triyajda doğru karar almalarına yol gösterici olabileceği bildirilmektedir. Ülkemizde henüz acil yardım ambulanslarında bu cihazlar kullanılmamaktadır. Yurt dışında ise portatif kompakt laktat analizörlerinin ambulanslarda bulunmasının ve laktatın uyarıcı ve yönlendirici bir biyobelirteç olarak kabul edilmesinin önemi vurgulanmaktadır.

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Hemorajik Ve İskemik Serebrovasküler Hastalık Tanısı Alan Hastalarda Kan Laktat Düzeyinin Prognoz Üzerine Etkisi

Cited by 2 publications

References 24 publications

Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short‐ and long‐term mortality risk

Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short‐ and long‐term mortality risk

A Parameter Affecting the Pre-Hospital Approach: Capillary Lactate Measurement

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