Hemopoietic Growth Factors and Oncogenes in Myeloid Leukemia Development

Metcalf, Donald

doi:10.1007/978-3-642-72624-8_4

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1998

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“…BAG␣ retroviral infection. Following several passages, proliferative spheres were triturated and after 2 days, infected by incubating the cells with the supernatant from the carrier cell line BAG␣ (ATTC) for 3 h as described previously (9,47). The supernatant was diluted 1:4 with progenitor cell expansion media and the cells were allowed to divide for 3 days.…”

Section: Methodsmentioning

confidence: 99%

“…Hematopoietic cytokines are a large group of proteins normally found in blood that are involved with clonal expansion and lineage restriction of stem and progenitor cells within the hematopoietic system (39,44,47). Many of these cytokines including erythropoietin (EPO), colony stimulating factor (CSF), and several members of the interleukin (IL) family are found within the brain and have been shown to influence the development of neurons (44).…”

Section: Introductionmentioning

confidence: 99%

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