“…The only adult study connected with this problem showed that patients with chronic bronchitis failed to develop increases in H influenzae hemagglutinating antibody following acute exacerba¬ tions, some of which were presumably due to H influenzae.20 In children, increases in agglutinating antibody have been reported after H influenzae bronchiolitis. These in¬ creases, however, have been transient, and sera studied eight weeks after the infection have no longer contained antibody.2 Three causes of a pyogenic arthritis are known: (1) direct trauma to the joint; (2) blood-borne infection; (3) extension from a neighboring area of infection such as an ad¬ jacent osteomyelitis. 1 Hematogenous dissemination was the most likely cause of the pyrathrosis in the four cases previously cited.…”