Abstract:Objective
Investigation of a Jr(a‐) family samples, identification of the mutant and assessment of the differences of Jr antigen density of the Jr(a‐) family members, random adult and newborn individuals' RBCs.
Background
The anti‐Jra antibody is generated when a Jr(a‐) individual pregnant or transfused with Jr(a+) blood unit, which can lead to mild‐to‐moderate hemolytic disease of the foetus and newborn (HDFN) or hemolytic transfusion reaction (HTR). Several mutations had been identified. The anti‐Jra caused … Show more
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