1999
DOI: 10.1253/jcj.63.400
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Hemolytic Anemia in Native Valve Infective Endocarditis

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Cited by 12 publications
(10 citation statements)
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“…There are reports of fragmentation hemolysis related to acute infective endocarditis of the native valve (4,5). The present case was not comparable with previous reports because the patient had had infective endocarditis 16 years previously.…”
Section: Discussioncontrasting
confidence: 86%
“…There are reports of fragmentation hemolysis related to acute infective endocarditis of the native valve (4,5). The present case was not comparable with previous reports because the patient had had infective endocarditis 16 years previously.…”
Section: Discussioncontrasting
confidence: 86%
“…It was hypothesized that vegetation on the valves can apply shearing stress on RBC leading to fragmentation similar to valve‐related mechanical hemolytic anemia particularly prosthetic mitral valve regurgitation 5, 6, 7. The infectious microorganisms may also cause the production of anti‐erythrocyte antibodies by cross‐reaction with erythrocyte antigens, or by modification of the antigenicity of erythrocyte antigens or by unmasking antigens that are not normally available 5. Our case presentation was similar albeit with even more scant evidence.…”
Section: Discussion and Review Of Literaturementioning
confidence: 54%
“…Both mechanical hemolysis and autoimmune hemolysis have been described 2, 3, 4. Hsuan‐Li et al reviewed six cases of hemolytic anemia secondary to endocarditis; in all the cases, there was the presence of fragmented erythrocytes suggestive of intravascular hemolysis 5. Interestingly, multiple cases also demonstrated the co‐existing immune‐mediated mechanism, evidenced by the presence of spherocytes, splenomegaly, and a positive direct Coombs test 5.…”
Section: Discussion and Review Of Literaturementioning
confidence: 99%
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