Hemolysis, Renal Failure, and Local Necrosis Following Scorpion Sting

Chadha, J. S.

doi:10.1001/jama.1979.03290360054029

Cited by 17 publications

(5 citation statements)

References 6 publications

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“…However, these levels may require further study, because secondary renal failures due to scorpion stings have been reported by several authors in Khuzestan. Increasing BUN and CR levels in sting victims are good markers of renal failure following a scorpion sting ( Chadha and Leviav 1979 ; Malhotra et al 1978 ; Radmanesh 1990a , b ).…”

Section: Discussionmentioning

confidence: 99%

The Roles of Some Scorpions,Hemiscorpius lepturusandAndroctonus crassicauda, in a Scorpionism Focus in Ramhormorz, Southwestern Iran

Mohseni

Vazirianzadeh

Hossienzadeh

et al. 2013

Journal of Insect Science

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Scorpion stings are a common and important health problem in Iran, particularly in south and southwestern Iran, including the province of Khuzestan. In the area of Khuzestan near the city of Ramhormoz, Hemiscorpius lepturus (Scorpionida: Hemiscorpioiidae) and Androctonus crassicauda (Buthidae) are present. Ramhormoz is in southwestern Iran and is one of the most important foci of the scorpion sting problem. The current study was carried out to gain both epidemiological and medical information about scorpion stings in and around the city of Ramhormoz. In total, 179 people who were admitted to the Emergency Department of Ramhormoz Imam Khomeini Hospital during 2008 and 2009 after being stung by scorpions were monitored. Epidemiological and medical parameters including sex of the victim; the part of the body stung; the month when stung; the biochemical parameters comprising blood sugar (BS), blood urea nitrogen (BUN), and creatinine (CR); hematological parameters including white blood cells (WBC), count blood cells (CBC), red blood cells (RBC), hemoglobin (Hb), hematocrit (HCT), platelet (PLT); and urine analysis including hemoglobinuria were recorded. The current study showed that most of the victims were stung by H. lepturus, while very few were stung by A. crassicaud, but in over half of the cases the species was not known. Stings were most common from May to Aguust. 73% of the victims were female. The limbs were the part of the body most likely to be stung. Hemogobinuria was very common in H. lepturus victims.

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Section: Discussionmentioning

confidence: 99%

The Roles of Some Scorpions,Hemiscorpius lepturusandAndroctonus crassicauda, in a Scorpionism Focus in Ramhormorz, Southwestern Iran

Mohseni

Vazirianzadeh

Hossienzadeh

et al. 2013

Journal of Insect Science

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“…The direct toxic effect of venom could cause interstitial nephritis, release of cytokines and the vasodilatation may lead to ischemic tubular necrosis 43 . However, the renal failure is most likely not a direct nephrotoxic effect 45 , which remains to be investigated. Accordingly, some pathologic data from kidney biopsies revealed the association of these factors, such as direct nephrotoxicity of venom, haemoglobinuria, secondary to microvascular hemolysis and hypovolemia 28 , 43 .…”

Section: Discussionmentioning

confidence: 99%

“…Most reports about AKI due to scorpion stings are from Asia (Iran, Tunisia, Pakistan, Turkey and Israel) 15 , 40 , 42 , 45 - 49 , and are more common in pediatric patients, as summarized in Table 3 . Most patients developed AKI in the setting of hypovolemia and cardiac failure, associated with acute tubular necrosis, pigmenturia, hemolytic uremic syndrome or interstitial nephritis, besides hemolysis 15 .…”

Section: Discussionmentioning

confidence: 99%

Acute kidney injury and pancreatitis due to scorpion sting: case report and literature review

Albuquerque

Magalhaes²,

Sales³

et al. 2018

Rev. Inst. Med. trop. S. Paulo

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Despite the high number of accidents due to scorpion stings in Brazil, severe cases in adults are seldomly reported. In the Northeast region of Brazil, Tityus stigmurus is the most prevalent species. A 69 year-old woman who was stung by a scorpion attended the emergency room 5 hours after envenomation. She got worse due to abdominal pain. Clinical findings were concordant with class III scorpion envenomation (major systemic manifestations), complicated by acute kidney injury and acute pancreatitis. Intensive supportive therapy was adopted. In the follow-up, 3 months later, she was completely recovered. This report is being brought to recommend the thorough management of victims of scorpion accidents, enabling early diagnosis of severe complications, which could lead to death if aggressive supportive measures are not early and adequately taken.

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“…Direct venom toxicity to the tissues due to high molecular weight substances like hyaluronidase and sphingomyelinase is reported, potassium channel toxins may mediate vascular contraction by causing smooth muscle depolarization and hence afferent arteriolar vasoconstriction, systemic inflammatory response syndrome, complement activation, myocarditis and adrenergic mediated vasoconstriction may all reduce renal blood flow [6]. In addition haemoglobinuria-related pigment nephropathy [7], haemolytic uraemic syndrome [8] and acute interstitial nephritis [9] are also reported as causes of acute renal failure.…”

Section: Discussionmentioning

confidence: 99%

Nephrotic syndrome after scorpion sting

et al. 2015

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Scorpion venom is a water soluble, antigenic and heterogeneous mixture. The venom is composed of varying concentration of neurotoxin, cardiotoxin, nephrotoxin, haemolytic toxin, phosphodiesterase, phospholipases, hyaluronidases, glycosaminoglycans, histamine, serotonins, and tryptophan and cytokine releasers. The reported incidence of scorpion sting in India is 0.6 %. Scorpion sting resulting in acute renal failure has been reported in the past, but not the nephrotic syndrome. We report a patient of nephrotic syndrome after scorpion sting. The lacunae in the present knowledge linking scorpion sting venom with nephrotic syndrome would only be replete with publications of similar reports.

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Hemolysis, Renal Failure, and Local Necrosis Following Scorpion Sting

Cited by 17 publications

References 6 publications

The Roles of Some Scorpions,Hemiscorpius lepturusandAndroctonus crassicauda, in a Scorpionism Focus in Ramhormorz, Southwestern Iran

The Roles of Some Scorpions,Hemiscorpius lepturusandAndroctonus crassicauda, in a Scorpionism Focus in Ramhormorz, Southwestern Iran

Acute kidney injury and pancreatitis due to scorpion sting: case report and literature review

Nephrotic syndrome after scorpion sting

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