Hemoglobin levels and 30-day mortality in patients after myocardial infarction

Lipšic, Erik; Horst, Iwan C. C. van der; Voors, Adriaan A.; Meer, Peter van der; Nijsten, Maarten W. N.; Gilst, Wiek H. van; Veldhuisen, Dirk J. van; Zijlstra, Felix

doi:10.1016/j.ijcard.2004.10.043

Cited by 72 publications

(47 citation statements)

References 29 publications

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“…Anemia was present in 28% of the ACS patients studied confirming that anemia is frequently found in patients with ACS, although the prevalence varies widely between 10% to 30% depending on the definition used in various studies. [1][2][3][4][5][6][7][8][9] In accordance with the findings linking anemia and poor clinical outcomes in ACS patients, this study demonstrated that ACS patients with anemia were more likely to be older, female, and associated with comorbidities like diabetes, hypertension, chronic renal failure, and stroke; [1][2][3][4][5][6][7][8][9]18,19 thus identifying a high-risk population with poor hematopoetic reserve. They were more likely to present with lower systolic blood pressure, higher heart rates, and higher Killip class and GRACE risk scores.…”

Section: Discussionsupporting

confidence: 78%

“…One of the main findings of the present study is that admission anemia during ACS was not only related to statistically significant higher in-hospital mortality, 2,8,18 but also predicted 1-month 1,3,11,18 and 1-year mortality. [5][6][7]9,[23][24][25][26] The multiple regression models showed that this relationship persisted even after adjustment with GRACE risk score.…”

Section: Mortalitysupporting

confidence: 49%

“…[1][2][3][4][5][6][7][8][9] In addition, the need for blood transfusion due to anemia in the setting of ACS is associated with higher short-term mortality. 10 Furthermore, a low baseline hemoglobin level in ACS patients has been found to be an independent predictor of the risk of in-hospital major bleeding and risk of death and myocardial infarction at 30 days.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Impact of Anemia on In-Hospital, One-Month and One-Year Mortality in Patients with Acute Coronary Syndrome from the Middle East

Sulaiman¹,

Panduranga²,

Al‐Zakwani³

et al. 2012

Clinical Medicine & Research

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Section: Discussionsupporting

confidence: 78%

Section: Mortalitysupporting

confidence: 49%

mentioning

confidence: 99%

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Impact of Anemia on In-Hospital, One-Month and One-Year Mortality in Patients with Acute Coronary Syndrome from the Middle East

Sulaiman¹,

Panduranga²,

Al‐Zakwani³

et al. 2012

Clinical Medicine & Research

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“…Both anemia and DM are recognized as strong independent risk factors for mortality and recurrent ischemia after acute MI. 45,46 Anemia is 2-3 times more common in indivisuals with DM compared to those without DM 6 . Recent studies have shown that anemia is associated with increased short term mortality in patients with IHD.…”

Section: Discussionmentioning

confidence: 99%

Anemia its presence and severity in type 2 DM and its relationship with micro and macro vascular complications

Manglunia¹

2018

jmscr

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“…Anemia, an independent predictor of mortality after ACS, is seen in approximately 15% of patients presenting with ACS, and the incidence goes up to 43% in elderly patients (4,5) . The ACUITY trial demonstrated that the presence of anemia on admission in patients with NSTE-ACS is associated with both short and long-term adverse events and increased 1-year mortality (6) .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Relationship Between Hemoglobin Levels and Thrombolysis in Myocardial Infarction Risk Score in Patients with Non-ST Elevation Acute Coronary Syndrome

Geçmen¹,

Güler²,

Güler³

et al. 2016

Kosuyolu Heart Journal

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Introduction:The relationship between hemoglobin (Hb) levels at admission and the thrombolysis in myocardial infarction (TIMI) risk score in patients with non-ST elevation acute coronary syndrome (NSTE-ACS) was investigated. Patients and Methods:In total, 286 NSTE-ACS patients were included in the study. Hb levels and biochemical parameters were measured at admission. The patients were grouped into the following three groups according to the TIMI risk score: low-intermediate-, and high-risk groups.Results: Hb levels (in g/dL) at admission in low-, intermediate-, and high-risk groups were 13.5 ± 1.9, 12.5 ± 1.9, and 11.3 ± 1.9, respectively (p < 0.001). We found a negative moderate correlation between Hb levels and TIMI risk scores (r= -0.408, p < 0.001). In univariate regression analysis, it was found that with the increase in the TIMI risk score, Hb levels at admission were signifi cantly reduced (estimate= -0.406; p< 0.001; 95% confi dence interval; -0.521 to -0.290). Conclusion:We found that as the TIMI risk score of patients admitted to hospital presenting with NSTE-ACS increased, their Hb levels at admission correspondingly decreased. Thus, the simple and commonly measured Hb level can be a useful parameter in stratifying the risks of patients presenting with NSTE-ACS during admission.Key Words: Myocardial infarction; hemoglobins; acute coronary syndrome ST Yükselmesiz Akut Koroner Sendrom Hastalarında TIMI Risk Skoru ile Hemoglobin Değeri Arasındaki İlişkinin Değerlendirilmesi ÖZETGiriş: ST yükselmesiz akut koroner sendrom hastalarının geliş hemoglobin seviyesi ile TIMI risk skoru arasındaki ilişki araştırıldı. Hastalar ve Yöntem:ST yükselmesiz akut koroner sendromlu 286 hasta çalışmaya dahil edildi. Tüm hastaların geliş anında hemoglobin ve biyokimyasal parametreleri çalışıldı. Hastalar TIMI risk skoruna göre düşük, orta ve yüksek risk olarak 3 gruba ayrıldı.Bulgular: Geliş hemoglobin seviyesi (g/dL) düşük, orta ve yüksek TIMI risk grubunda sırasıyla (13.5 ± 1.9, 12.5 ± 1.9, 11.3 ± 1.9, p< 0.001) olarak saptandı. Hemoglobin seviyesi ve TIMI risk skoru arasında orta dü-zeyde negatif korelasyon bulundu (r: -0.408, p< 0.001). Tek değişkenli regresyon analizinde TIMI risk skoru artışı ile geliş hemoglobin seviyelerinin önemli derecede düşük olduğu saptandı (Estimate; -0.406, p< 0.001, %95 GA [-0.521-(-0.290 )].Sonuç: ST yükselmesiz akut koroner sendrom ile hastaneye yatırılan hastaların risk skoru attıkça geliş hemoglobin seviyelerinin bağlantılı olarak düşük olduğu tespit edildi. Basit ve yaygın bir test olarak kullanılan hemoglobin seviyesi, ST yükselmesiz akut koroner sendrom hastalarının geliş anındaki risk durumunu belirlemede kullanılabilir.

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Hemoglobin levels and 30-day mortality in patients after myocardial infarction

Cited by 72 publications

References 29 publications

Impact of Anemia on In-Hospital, One-Month and One-Year Mortality in Patients with Acute Coronary Syndrome from the Middle East

Impact of Anemia on In-Hospital, One-Month and One-Year Mortality in Patients with Acute Coronary Syndrome from the Middle East

Anemia its presence and severity in type 2 DM and its relationship with micro and macro vascular complications

Evaluation of the Relationship Between Hemoglobin Levels and Thrombolysis in Myocardial Infarction Risk Score in Patients with Non-ST Elevation Acute Coronary Syndrome

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