Hemoglobin heterogeneity in Amazonian fishes

Fyhn, Unni E. H.; Fyhn, Hans Jørgen; Powers, Dennis A.; Fink, William L.; Garlick, Robert

doi:10.1016/0300-9629(79)90740-0

Cited by 140 publications

(68 citation statements)

References 23 publications

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“…ND, no data; 0, no effect; ϩ, significant increase; Ϫ, significant decrease. large survey on hemoglobins of 77 Amazon fish, Fyhn et al (3) showed an average of four different hemoglobins per species. Of the 16 cichlid species investigated, the numbers ranged between five and nine different hemoglobins.…”

Section: Discussionmentioning

confidence: 99%

Multiple strategies of Lake Victoria cichlids to cope with lifelong hypoxia include hemoglobin switching

Rutjes

Nieveen²,

Weber³

et al. 2007

American Journal of Physiology-Regulatory, Integrative and Comp

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Many fish species adapt to hypoxia by reducing their metabolic rate and increasing hemoglobin-oxygen (Hb-O2) affinity. Pilot studies with young broods of cichlids showed that the young could survive severe hypoxia in contrast with the adults. It was therefore hypothesized that early exposure results in improved oxygen transport. This hypothesis was tested using split brood experiments. Broods of Astatoreochromis alluaudi, Haplochromis ishmaeli, and a tilapia hybrid ( Oreochromis) were raised either under normoxia (NR; 80–90% air saturation) or hypoxia (HR; 10% air saturation). The activity of the mitochondrial citrate synthase was not different between NR and HR tilapia, but was significantly decreased in HR A. alluaudi and H. ishmaeli, indicating lowered maximum aerobic capacities. On the other hand, hemoglobin and hematocrit levels were significantly higher in all HR fish of the three species, reflecting a physiological adaptation to safeguard oxygen transport capacity. In HR tilapia, intraerythrocytic GTP levels were decreased, suggesting an adaptive increase of blood-O2 affinity. Similar changes were not found in HR H. ishmaeli. In this species, however, all HR specimens exhibited a distinctly different iso-Hb pattern compared with their NR siblings, which correlated with a higher intrinsic Hb-O2 affinity in the former. All HR cichlids thus reveal left-shifted Hb-O2 equilibrium curves, mediated by either decreased allosteric interaction or, in H. ishmaeli, by the production of new hemoglobins. It is concluded that the adaptation to lifelong hypoxia is mainly due to improved oxygen transport.

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Section: Discussionmentioning

confidence: 99%

Multiple strategies of Lake Victoria cichlids to cope with lifelong hypoxia include hemoglobin switching

Rutjes

Nieveen²,

Weber³

et al. 2007

American Journal of Physiology-Regulatory, Integrative and Comp

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“…The majority of teleosts possess polymorphic hemoglobin systems (Fyhn et al 1979), and adjustments in isomorph abundances are a common theme of acclimation (Houston 1980). Accordingly, considerable emphasis has been given to their adaptive potential.…”

Section: Hemoglobin Isomolphismmentioning

confidence: 99%

Hematological response in fish: pronephric and splenic involvements in the goldfish,Carassius auratus L.

Houston

Roberts

Kennington

1996

Fish Physiol Biochem

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Pronephric and splenic involvements in erythropoiesis and in stress-induced hematological response by goldfish,Carassius auratus, were examined under conditions of minimal stress and following transient (3h) temperature-induced elevation of O2 demand and transient (3h) exposure to hypoxia. Although hemoglobin content and red cell numbers were little affected, the ontogenic composition of the circulating erythrocyte population was significantly altered by both types of respiratory challenge and also by the stresses associated with capture, air exposure during transfer and intraperitoneal administration of label. Juvenile cell numbers increased sharply while mature erythrocyte abundances declined. Consistent with this, [(3)H] methylthymidine-labeled cell numbers rose in both spleen and pronephros following imposition of stress. Splenic erythropoietic activity was modest relative to that of the pronephros. Our observations point to a readily triggered response involving: [1] release of cells reservoired in the spleen and pronephros, [2] increased erythropoiesis and [3] karyorrhexis. We suggest that while the magnitude of response may depend on the quality and magnitude of the imposed stress, its central features are essentially constant.

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“…De tal manera que ciertas hemoglobinas específicas aisladas de hemolisados, posiblemente afectarían la sobrevivencia durante alguna fase de la vida de los peces amazónicos, pero una conexión directa entre una hemoglobina específica y una bien definida presión de selección aun no se ha demostrado (FYHN et al, 1979); No obstante, estudios de peces en la cuenca amazónica cuestionan, la significancia de la temperatura como un factor importante, responsable de la heterogeneidad de la hemoglobina, reportando mayor número de hemoglobinas, en peces provenientes de ambientes termolábiles, en comparación con peces de ambientes termoestables (FYHN et al, 1979). PÉREZ et al (1985) demostraron que el número promedio de hemoglobinas y la incidencia de polimorfismo es similar en peces tropicales y extratropicales.…”

Section: Polimorfismo De Longitud De Fragmentos Amplificados (Aflp)unclassified

<htm>Diversidad Genética del Bocachico (<i>Prochilodus reticulatus</i>) de la Cuenca Alta del Río Cauca (Colombia)</htm>

MacÍAs

Vallejo

Rincón³

et al. 2009

ABPar

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Hemoglobin heterogeneity in Amazonian fishes

Cited by 140 publications

References 23 publications

Multiple strategies of Lake Victoria cichlids to cope with lifelong hypoxia include hemoglobin switching

Multiple strategies of Lake Victoria cichlids to cope with lifelong hypoxia include hemoglobin switching

Hematological response in fish: pronephric and splenic involvements in the goldfish,Carassius auratus L.

<htm>Diversidad Genética del Bocachico (<i>Prochilodus reticulatus</i>) de la Cuenca Alta del Río Cauca (Colombia)</htm>

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