Hemoglobin determination in blood donors

Cable, Ritchard G.

doi:10.1016/s0887-7963(05)80052-5

Cited by 54 publications

(57 citation statements)

References 69 publications

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“…The activity of SOD in erythrocytes was determined by the method described by Madesh and Balasubramanian (28). The total antioxidant status (TAS) was measured colorimetrically as reported (5), and hemoglobin, by the method previously described (29).…”

Section: Antioxidant Statusmentioning

confidence: 99%

Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

et al. 2017

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Background: Previously has been reported the antioxidant function of iodine, and iodine deficiency as a risk factor of preeclampsia.Aim: We analyze the association between iodine deficiency, oxidative stress and antioxidant status with hypertensive disease of pregnancy (HPD).Method: 57 pregnant women were recruited in the last trimester of pregnancy, 20 diagnosed with hypertensive disease of pregnancy and 37 normotensive pregnant women. Urinary iodine concentration (UIC), TSH, free T4 (fT4), total antioxidant status (FRP), Superoxide dismutase (SOD), Catalase (CAT), and oxidative stress (TBARS) were evaluated by colorimetric methods.Results: UIC median for all pregnant women was of 151.9 µg / L. The UIC median for pregnant women with HPD was between 50-149 µg/L compared to 150-249 µg/L in normotensive women. No significant changes were found in levels of TSH and fT4 in normotensive pregnant compared with HPD women. Pregnant women with HPD had significant high levels of TBARS, and significant low levels of FRP, SOD, CAT and UIC compared to normotensive pregnant. In addition, pregnant women with optimal levels of UIC had a higher SOD activity (R = 0.354, P = 0.011), while iodine deficiency was associated with HPD (R = -0,281, p = 0.039). Similarly, pregnant with HPD had a significant negative association with SOD activity (R = -0,702, p = 0.005), CAT (R = -0,409, p = 0.002), and FRP (R = -0,624, p = 0.003), and a positive association with TBARS (R = 0.744, p = 0.001).Conclusion: iodine contributes to REDOX balance during pregnancy; its deficiency is associated with HPD. This study shows the importance of iodine during pregnancy.

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Section: Antioxidant Statusmentioning

confidence: 99%

Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

et al. 2017

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“…In the United States, the FDA-mandated criteria are controversial but have remained unchanged at 12.5 g/dL for both men and women since 1958 [21CFR 640.3(b)] [3], although they have been publicly debated on several occasions [23][24][25][26]. The practical effect of having a single Hb cutoff of 12.5 g/dL is that women are preferentially affected by the criteria, resulting in the deferral of about 1 in 7 women who present to donate and accounting for majority (>90%) of hemoglobin deferrals (Table I).…”

Section: Donor Hemoglobin and Donation Intervalmentioning

confidence: 99%

Evidence‐based selection criteria to protect blood donors

Eder

2010

J of Clinical Apheresis

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A safe and adequate blood supply depends on healthy, volunteer blood donors. Blood centers have instituted various screening procedures in an effort to determine that donors are free of diseases that can be transmitted to patients by blood transfusion and are able to tolerate the collection procedure without experiencing significant complications. This review focuses on selection criteria intended to minimize the risk to the blood donor. Defining a rational, evidence-based approach to donor selection is crucial not only to take reasonable precautions to protect the donors' health but also to eliminate practices that lead to the unnecessary deferral of large numbers of people without improving the safety of the donation process. Donor selection criteria, including predonation pulse and blood pressure, donor weight and total blood volume, minimum hemoglobin and donation interval, are considered against the available evidence that support or suggest the need to modify the current approach to protect blood donor health.

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“…Several studies performed on American blood donors have attested to the good reproducibility and accuracy of the HemoCue method. 4,5 However, comparability of the Hb level measured via the HemoCue method with other, more recently available hematological equipment has not been performed. In this study we reviewed the performance of the HemoCue system in comparison with the Coulter and Cobas methods.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of three methods for hemoglobin measurement in a blood donor setting

et al. 1999

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CONTEXT: The hemoglobin (Hb) level is the most-used parameter for screening blood donors for the presence of anemia, one of the most-used methods for measuring Hb levels is based on photometric detection of cyanmetahemoglobin, as an alternative to this technology, HemoCue has developed a photometric method based on the determination of azide metahemoglobin. OBJECTIVE: To evaluate the performance of three methods for hemoglobin (Hb) determination in a blood bank setting. DESIGN: Prospective study utilizing blood samples to compare methods for Hb determination. SETTING: Hemotherapy Service of the Hospital Israelita Albert Einstein, a private institution in the tertiary health care system. SAMPLE: Serial blood samples were collected from 259 individuals during the period from March to June 1996. MAIN MEASUREMENTS: Test performances and their comparisons were assessed by the analysis of coefficients of variation (CV), linear regression and mean differences. RESULTS: The CV for the three methods were: Coulter 0.68%, Cobas 0.82% and HemoCue 0.69%. There was no difference between the mean Hb determination for the three methods (p>0.05). The Coulter and Cobas methods showed the best agreement and the HemoCue method gave a lower Hb determination when compared to both the Coulter and Cobas methods. However, pairs of methods involving the HemoCue seem to have narrower limits of agreement (± 0.78 and ± 1.02) than the Coulter and Cobas combination (± 1.13). CONCLUSION: The three methods provide good agreement for hemoglobin determination.

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Hemoglobin determination in blood donors

Cited by 54 publications

References 69 publications

Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

Evidence‐based selection criteria to protect blood donors

Evaluation of three methods for hemoglobin measurement in a blood donor setting

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