Hemoglobin AC retinopathy managed with vitrectomy and adjunctive bevacizumab

Hemoglobin C Trait Presenting With Bilateral Central Retinal Vein Occlusion

“…8 Ten cases of hemoglobin C trait retinopathy have been described; interestingly, most of these reports have all been in individuals with comorbidities such as hypertension. [9][10][11][12][13] The etiology of CRVO in hemoglobin C trait is believed to involve a synergistic mechanism between hemoglobin C and hypertension leading to occlusive microangiopathy. 12 Prior authors have noted cases of peripheral vascular occlusion, vitreous hemorrhage, and retinal neovascularization, but to our knowledge, this is the first report of bilateral CRVO in an individual with hemoglobin C trait.…”