Hemofiltration in Childhood

Use of Hemodiafiltration in Children

“…Treatment time per session is usually 3 hr (3 x 3 hrlweek) and is primarily dependent upon body weight loss per session (to reach dry body weight) rather than on cleared volume (clearance per session time; K mL/min X t min). Despite cardiovascular stability induced by the HF effects (8,9) of HDF (plasma osmolality stability secondary to high replacement fluid rate infusion), the mean body weight loss per hour is limited to 1.6% * 0.5% (10,11).…”

Effects of 1,25-Dihydroxyvitamin-D3 Treatment on Mineral Balance in Children with End Stage Renal Disease Undergoing Chronic Hemofiltration

“…The mean total phosphate removed per H F run was 574 mg. We conclude that even though a calcium gain and a high phosphate removal was obtained with our H F prescription, secondary hyperparathyroidism in children on chronic H F may be maintainued under control if 1,25 There are many reports of long-term 1,25(OH)2D3 treatment of children with ESRD with and without chronic HD or chronic ambulatory peritoneal dialysis (1-7). However, there has been no study of such treatment in children on chronic HF, a replacement method based on convective transport (8) recently introduced in children (9). This method has been reported to be more effective than HD in removing toxins of middle and large molecular weight (10) and in reducing hypotension and other symptoms of dialysis intolerance in uremic adults and children (9, 1 [1][2][3][4][5][6][7][8][9][10][11][12][13].…”

“…However, there has been no study of such treatment in children on chronic HF, a replacement method based on convective transport (8) recently introduced in children (9). This method has been reported to be more effective than HD in removing toxins of middle and large molecular weight (10) and in reducing hypotension and other symptoms of dialysis intolerance in uremic adults and children (9, 1 [1][2][3][4][5][6][7][8][9][10][11][12][13]. HF has been variously claimed to improve (l3), worsen (14), or not change (15) hyperparathyroidism in uremic adults.…”