Hemodynamic Effects of Different Vasopressors (Etilefrine, Norfenefrine, Akrinor, Amezinium Metilsulfate) During Hypotension Caused by Epidural Anesthesia

Müller, H; Brähler, A.; Stoyanov, M.; Gerlach, Irene; Hempelmann, G.

doi:10.1007/978-3-642-70807-7_13

Cited by 1 publication

(1 citation statement)

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“…A similar bimodal effect may be observed after application of certain vasopressors, e.g., after etilefrine, a sympathomimetic drug which stimulates a and p receptors. The initial P2 effect becomes especially obvious if this drug is used to treat hypotension during epidural anaesthesia [23]. It is interesting that etile frine also exhibits tocolytic activity [24], To avoid an unwanted decrease of blood pressure during tocolysis following cervix cerclage in spinal anaesthesia it may be useful to restrict the spread of blockade by position ing the patient head-up, thus achieving a socalled 'saddle block'.…”

Section: Discussionmentioning

confidence: 99%

Haemodynamic Effects of Fenoterol for Labour Inhibition during Spinal or Epidural Anaesthesia

Müller¹,

Gips

Brähler³

et al. 1985

Gynecol Obstet Invest

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Haemodynamic investigations, partly using invasive monitoring, concerning interactions between the Β-mimetic effect of fenoterol and the Α-sympathetic blockade of spinal or epidural anaesthesia were made in a total of 49 patients during pregnancy, during cae-sarean section and in non-pregnant women. Haemodynamic effects of fenoterol during regional anaesthesia were compared with those during general anaesthesia (n = 17). Epidural or spinal anaesthesia enhance vascular Β-mimetic reactions at the start of tocolysis, leading to a profound but short-lasting decrease in blood pressure. This initial hypotension is more pronounced after regional than after general anaesthesia.

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Section: Discussionmentioning

confidence: 99%