Hemodynamic Effects of an Irregular Sequence of Ventricular Cycle Lengths During Atrial Fibrillation

Abstract

An irregular sequence of RR intervals produces adverse hemodynamic consequences that are independent of heart rate.

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

“…In addition to the average rate, the irregularity of electrical activation may have important cardiovascular effects [33]. An irregular pacing interval causes decreased cardiac output, as well as increased pulmonary wedge and right atrial pressure compared to regular pacing at the same rate in patients [7]. In another cohort, greater degrees of irregularity have been associated with increased sympathoexcitation [26].…”

Blood pressure measurement in patients with rate controlled atrial fibrillation using mercury sphygmomanometer and Omron HEM-750CP deice in the clinic setting

“…8 It is important to measure blood pressure accurately in patients with AF. 9,10 We compared the use of mercury sphygmomanometer and Omron HEM-750CP in 20 patients with AF, group matched for age and sex with 20 subjects in SR in a clinic setting. Both devices are recommended by the ESH.…”

“…9,10 In AF, the variability with manual readings may be higher due to observer expectation of variability and a greater possibility of clinician error in listening to the first sound compared to SR. 10 Inter-observer variability has been shown to be higher than intra-observer variability with manual manometer for the systolic than the diastolic readings in sinus rhythm. This variability would be exaggerated in AF patients.…”

Optymalna rozbudowa dwujamowego układu stymulującego u pacjentki z utrwalonym migotaniem przedsionków

“…The irregularity of the heart rhythm itself during atrial fibrillation has a deleterious impact on the cardiac function. This concept was proved more than twenty years ago by Clark et al in an excellent experimental study in patients with atrial fibrillation undergoing the atrioventricular node ablation and the pacemaker implantation [7]. The authors concluded that an irregular sequence of RR intervals produces adverse hemodynamic consequences that are independent of the heart rate.…”