Hemodynamic Changes Associated with Hemodilution Priming of a Rotating Disc Oxygenator

Ankeney, Jay L.; Renner, Daniel; Leverett, F. Lynn; Beheler, Edward M.

doi:10.1016/s0003-4975(10)66736-7

Cited by 13 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The good news was apparent in later studies of Ankeney and colleagues, who, having documented the adverse influence of HB in canines undergoing CPB, observed that the pathophysiologic alterations did not occur when their large prime pump-oxygenator was primed with dextran. 6 In close agreement with the experimental observations, a pattern of early hypotension and hypovole-mia with sequestration of both red cells and plasma was observed in patients undergoing CPB with large volume perfusion equipment primed with a number of units of HB. 7 These alterations resembled the hemodynamic and volumetric patterns seen in dogs, but the severity and lethal nature of the canine anaphylactoid reaction was, fortunately, never seen in man.…”

Section: Homologous Blood and Perfusion Problemssupporting

confidence: 85%

Historical vignettes concerning cardiopulmonary bypass without homologous blood and perfusion hypothermia

Litwak

2003

Perfusion

View full text Add to dashboard Cite

The development of a predictable means of carrying out CPB employing a nonhemic prime with the potential for performance of the entire cardiac operation devoid of HB and, second, the extraordinary advantage of perfusion hypothermia in establishing conditions permitting a safe period of circulatory arrest are two important components of contemporary perfusion methodology. These advances--and others yet to be--represent a continuum of the vision and accomplishments of John Gibbon who--with his lovely wife, Mary, and distinguished colleagues--made clinical CPB a reality 50 years ago.

show abstract

Section: Homologous Blood and Perfusion Problemssupporting

confidence: 85%