Hemodiafiltration with On-Line Production of Bicarbonate Infusate

Canaud, Bernard; Nguyen, Quang-Linh; Polito, Cesare; Stec, F.; Mion, C

doi:10.1159/000417476

Cited by 19 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They underwent PD-HFR for 1 year (for a total of 889 treatments), performing three weekly sessions of 225 8 13 3 -32 mEq/l, glucose 5.55 mmol/l). The confi guration of PD-HFR is shown in fi gure 2 .…”

Section: Methodsmentioning

confidence: 99%

“…The results reported in the literature are positive as far as the quality of the liquids is concerned, the improvement of the purifi cation performances linked to the increase in Quf, the fi nancial and management savings as compared with commercial solutions and the good cost-benefi t ratio [2][3][4] . Online HDF provides the largest amount of purifi ed blood over a wide molecular weight spectrum achievable with present renal replacement therapies.…”

mentioning

confidence: 99%

See 1 more Smart Citation

One Year of Clinical Experience in Postdilution Hemofiltration with Online Reinfusion of Regenerated Ultrafiltrate

et al. 2004

View full text Add to dashboard Cite

Background/Aims: Hemofiltrate reinfusion (HFR) is characterized by the use of regenerated ultrafiltrate as replacement fluid. We set up a new technique, postdilution HFR (PD-HFR), aiming at increasing purification efficiency, treatment tolerance and at reducing inflammatory states. Methods: We performed PD-HFR in 6 uremic patients during 1 year. Dialysis efficacy, dialyzer blood loss and the behavior of cytokines were evaluated. Results: No pyrogenic reactions or other adverse events were recorded. Treatment tolerance was excellent. We observed high urea extraction rates and optimal Kt/V values, high β₂-microglobulin (β₂m) extraction rates and a decrease in dialyzer blood loss; also IL-6 and TNF-α decreased significantly. Conclusions: Inversion of the standard HFR configuration has allowed us to improve the removal of both urea and β₂m, and to decrease dialyzer blood loss, with an optimal tolerance. Moreover, the decrease in cytokine levels might attenuate the uremic microinflammatory state.

show abstract

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%