Hemodiafiltration beneficially affects QT interval duration and dispersion compared to hemodialysis

Barta, K; Czifra, Árpád; Kun, Csaba; Páll, Alida; Kulcsar, J.; Paragh, György; Láng, István; Padra, Tamás János; Agarwal, Anupam; Zarjou, Abolfazl; Balla, József; Szabó, Zoltán

doi:10.1007/s10157-014-0950-9

Cited by 7 publications

(5 citation statements)

References 20 publications

(20 reference statements)

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“…Furthermore, we investigated the ECG parameters representing ventricular repolarization in the case of 30 patients receiving hemodiafiltration (HDF) over a period of 3 months, and we obtained data from the same patients after treatment with conventional hemodialysis (HD) for at least another 3 months. The duration of the QT interval and QT dispersion was only increased significantly in the case of HD, but no similar significant prolongations in the case of HDF could be observed (Figure 6) [66].…”

Section: Changes In Qt Interval and Qt Dispersion In Hyperlipidemia Amentioning

confidence: 80%

The Role of Electrocardiographic Markers in the Prevention of Atrial and Ventricular Arrhythmias

Sebestyén¹,

Szabó²

2016

Echocardiography in Heart Failure and Cardiac Electrophysiology

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In our chapter, we overview the main clinical conditions that increase arrhythmogenicity, and we present the surface electrocardiogram (ECG) markers that could be suitable for the prediction of atrial and ventricular arrhythmias. We highlight the clinical value of the prolongation of the P-wave duration and P dispersion (Pd) in the prediction of atrial fibrillation, and we also expound the utility of QT interval, T-wave peak-to-end interval (Tpe), and Tpe/QT ratio (known as arrhythmogenic index (AIX)) in the prediction of ventricular arrhythmias. Furthermore, we present the results of our clinical investigations with regard to surface ECG markers among patients with increased arrhythmia vulnerability. Moreover, we mention other, novel, effectively used ECG markers.

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Section: Changes In Qt Interval and Qt Dispersion In Hyperlipidemia Amentioning

confidence: 80%

The Role of Electrocardiographic Markers in the Prevention of Atrial and Ventricular Arrhythmias

Sebestyén¹,

Szabó²

2016

Echocardiography in Heart Failure and Cardiac Electrophysiology

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“…In addition to these known factors, it could also be hypothesized that patients receiving convective treatment for their renal diseases may benefit from a reduction in the incidence of arrhythmias and from the slower progression of damage to the heart [22,23]. Previously, we have demonstrated the beneficial effects of hemodiafiltration on ventricular repolarization, but the possible influence of this treatment modality on atrial rhythm disturbances has remained to be elucidated [24]. To clarify this hypothetical relationship between convective treatment and atrial arrhythmogeneity we decided to investigate atrial electrocardiographic arrhythmia markers during hemodiafiltration and hemodialysis.…”

Section: Discussionmentioning

confidence: 99%

Hemodiafiltration and hemodialysis differently affect P wave duration and dispersion on the surface electrocardiogram

et al. 2015

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“…Increased QT dispersion, showing a repolarization heterogeneity, has been reported in several pathological conditions; its predictive value for an arrhytmia risk and SCD has been confirmed in the cases of amyloidosis, hyperlipidemia, systemic sclerosis, thyroid dysfunction, diabetes mellitus, and chronic kidney disease (Sgreccia et al, 1998;Lőrincz et al, 1999;Cardoso et al, 2001;Szabó et al, 2005;Bakiner et al, 2008;Gilotra et al, 2013;Tse and Yan, 2017). Interestingly, when compared to hemodiafiltration QT dispersion has been found to be significantly higher during hemodialysis (Barta et al, 2014). In the case of patients with coronary artery disease increased QT dispersion had 92% sensitivity and 81% specificity in the prediction of SCD (Darbar et al, 1996).…”

Section: Electrocardiographic Estimation Of the Risk For Ventricular mentioning

confidence: 95%

Handling of Ventricular Fibrillation in the Emergency Setting

et al. 2020

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Ventricular fibrillation (VF) and sudden cardiac death (SCD) are predominantly caused by channelopathies and cardiomyopathies in youngsters and coronary heart disease in the elderly. Temporary factors, e.g., electrolyte imbalance, drug interactions, and substance abuses may play an additive role in arrhythmogenesis. Ectopic automaticity, triggered activity, and reentry mechanisms are known as important electrophysiological substrates for VF determining the antiarrhythmic therapies at the same time. Emergency need for electrical cardioversion is supported by the fact that every minute without defibrillation decreases survival rates by approximately 7%-10%. Thus, early defibrillation is an essential part of antiarrhythmic emergency management. Drug therapy has its relevance rather in the prevention of sudden cardiac death, where early recognition and treatment of the underlying disease has significant importance. Cardioprotective and antiarrhythmic effects of beta blockers in patients predisposed to sudden cardiac death were highlighted in numerous studies, hence nowadays these drugs are considered to be the cornerstones of the prevention and treatment of life-threatening ventricular arrhythmias. Nevertheless, other medical therapies have not been proven to be useful in the prevention of VF. Although amiodarone has shown positive results occasionally, this was not demonstrated to be consistent. Furthermore, the potential proarrhythmic effects of drugs may also limit their applicability. Based on these unfavorable observations we highlight the importance of arrhythmia prevention, where echocardiography, electrocardiography and laboratory testing play a significant role even in the emergency setting. In the following we provide a summary on the latest developments on cardiopulmonary resuscitation, and the evaluation and preventive treatment possibilities of patients with increased susceptibility to VF and SCD.

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Hemodiafiltration beneficially affects QT interval duration and dispersion compared to hemodialysis

Abstract: Background/Aims: The prolongation of the QT interval and dispersion could predict

Cited by 7 publications

References 20 publications

The Role of Electrocardiographic Markers in the Prevention of Atrial and Ventricular Arrhythmias

The Role of Electrocardiographic Markers in the Prevention of Atrial and Ventricular Arrhythmias

Hemodiafiltration and hemodialysis differently affect P wave duration and dispersion on the surface electrocardiogram

Handling of Ventricular Fibrillation in the Emergency Setting

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