Hemocompatibility of super-repellent surfaces: current and future

Movafaghi, Sanli; Wang, Wei; Bark, David; Dasi, Lakshmi Prasad; Popat, Ketul C.; Kota, Arun K.

doi:10.1039/c9mh00051h

Cited by 31 publications

(26 citation statements)

References 196 publications

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“…5 a Schematic diagram of hydrophilic modification. b Surface roughness for surface wetting models [ 66 ] …”

Section: Physicochemical Modification Of the Membrane Surfacementioning

confidence: 99%

Modification strategies to improve the membrane hemocompatibility in extracorporeal membrane oxygenator (ECMO)

Wang

et al. 2021

Adv Compos Hybrid Mater

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Since extracorporeal membrane oxygenator (ECMO) has been utilized to save countless lives by providing continuous extracorporeal breathing and circulation to patients with severe cardiopulmonary failure. In particular, it has played an important role during the COVID-19 epidemic. One of the important composites of ECMO is membrane oxygenator, and the core composite of the membrane oxygenator is hollow fiber membrane, which is not only a place for blood oxygenation, but also is a barrier between the blood and gas side. However, the formation of blood clots in the oxygenator is a key problem in the using process. According to the study of the mechanism of thrombosis generation, it was found that improving the hemocompatibility is an efficient approach to reduce thrombus formation by modifying the surface of materials. In this review, the corresponding modification methods (surface property regulation, anticoagulant grafting, and bio-interface design) of hollow fiber membranes in ECMO are classified and discussed, and then, the research status and development prospects are summarized. Graphical abstract

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“…5 a Schematic diagram of hydrophilic modification. b Surface roughness for surface wetting models [ 66 ] …”

Section: Physicochemical Modification Of the Membrane Surfacementioning

confidence: 99%

Modification strategies to improve the membrane hemocompatibility in extracorporeal membrane oxygenator (ECMO)

Wang

et al. 2021

Adv Compos Hybrid Mater

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“…70 Super-> 150°) △ < 5°) released due to the pressure of the liquid, there is a complete wetting, transitioning from Cassie state to the Wenzel state which is governed by breakthrough pressure. 73 This transition can make the surface more hydrophilic than the unmodified substrates due to the increase in overall roughness.…”

Section: Surface Properties and Their Influence In Hemocompatibilitymentioning

confidence: 99%

“…Super-repellent surfaces are surfaces that repel most liquids as their surface energy is significantly lower. 97 Although hydrophilicity has been widely employed for blood-contacting medical devices, recent research has shown even lower protein adsorption and platelet adhesion on superhydrophobic surfaces. 98 Superhydrophobicity can be achieved by combination of surface texture (e.g., micro and/or nanoscale texture) and coating with low surface energy compounds.…”

Section: Super-repellent Surfacesmentioning

confidence: 99%

Surface modification strategies to improve titanium hemocompatibility: a comprehensive review

et al. 2021

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“…Liquid-repellent surface technologies are studied extensively for a wide range of applications, such as waterproofing, anti-icing, antistaining, anti-biofouling and self-cleaning. [1][2][3][4][5][6] Superhydrophobic and superoleophobic surfaces are often prepared through a combination of topography, such as ordered arrays of nano-or microstructures or fibrous textures, and chemical functionality, fluorination, for example. 1,7 On these lotus-like surfaces, droplets interact with the surfaces and the air trapped between the features of the surfaces, resulting in discontinuous and unstable surface-liquid contact lines (Fig.…”

Section: Introductionmentioning

confidence: 99%

Covalently attached liquids as protective coatings

Melde

Malanoski

Moore

et al. 2020

Polymer International

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Covalently attached liquids provide a liquid-liquid surface interaction for contacting contaminants, typically achieved through use of a polydimethylsiloxane linear polymer bound to the surface at one end. The attached dimethylsiloxane polymer chain retains liquid-like mobility through bending and rotational motions, distinguishing the coatings from those formed by crosslinked polydimethylsiloxane or branched polymer chains. Here, covalently attached liquids are reviewed and their potential for application as topcoat treatments is discussed. This review focuses on a new use scenario: prevention of chemical contamination. When allowed to age in place, chemical contaminants tend to penetrate into painted surfaces. Standard decontamination processes can fail to remove the chemicals within the paint layer, resulting in secondary exposure hazards when environmental conditions change. Covalent liquid coatings provide repellency and shedding behaviors. This review highlights the failure of typical wetting evaluations in predicting performance for the new application as well as the potential of the coatings in enhancing chemical resistance for painted surfaces. Potential methods for further improvements are also discussed.

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Hemocompatibility of super-repellent surfaces: current and future

Abstract: In this review, we critically examine the progress made in characterizing the hemocompatibility of super-repellent surfaces and identify the potential challenges and opportunities for future research.

Cited by 31 publications

References 196 publications

Modification strategies to improve the membrane hemocompatibility in extracorporeal membrane oxygenator (ECMO)

Modification strategies to improve the membrane hemocompatibility in extracorporeal membrane oxygenator (ECMO)

Surface modification strategies to improve titanium hemocompatibility: a comprehensive review

Covalently attached liquids as protective coatings

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