Hemocompatibility improvement of poly(ethylene terephthalate) via self-polymerization of dopamine and covalent graft of zwitterions

Biomimetic surface modification of polypropylene by surface chain transfer reaction based on mussel-inspired adhesion technology and thiol chemistry

“…More importantly, the resultant polydopamine (PDA) film can act as a platform for easy and diverse secondary reactions to immobilize different functional groups [28][29][30][31][32][33]. It affords an opportunity to create a facial and versatile pathway for surface functionalization of PP.…”

“…In this study, based on the mussel-inspired adhesion technology [27][28][29][30][31][32][33] and the well-known high chain-transfer feature of thiol compounds [34], biomimetic surface modification of PP is conducted via surface chain transfer reaction (transferring radicals from the solution to surface-bonded thiol groups and re-initiating the polymerizationon PP surface) by using 2-methacryloyloxyethylphosphorylcholine (MPC) as a hydrophilic monomer mimicking the cell outer membrane structure and 2,2-azobisisobutyronitrile (AIBN) as initiator in ethanol. The resultant cell outer membrane mimetic structure surface (PP-PMPC) is expected to assume both good interfacial adhesion and blood compatibility.…”

In vitro and in vivo hemocompatibility evaluation of a new dermatan sulfate-modified PET patch for vascular repair surgery

“…Polyethylene terephthalate (PET) is one of the most important polymeric materials used in the biomedical field because of its good mechanical properties and stability . However, PET presents several limitations, mostly due to its synthetic origin, such as low blood‐compatible properties and moderate tissue inflammatory response . There is, therefore, a clear need for developing new PET‐based biomaterials with better hemocompatibility that will help avoiding the thrombosis risk at the site of injury.…”

Bioactive and Hemocompatible Calcium Sulphoaluminate Cement

“…The main requisites of a bioactive material are biocompatibility, appropriate mechanical properties and the ability to form an HA layer on its surface 6 . The application of biomaterials depends upon their interfacial properties and resultant interactions with cells and biological fluids in vivo 7 . The interaction of red blood cells with biomaterials or their extracts may be useful to evaluate the hemolytic activity of materials.…”