Hemiplegia Complicating Ophthalmic Zoster

Cope, S.; Jones, Allison

doi:10.1016/s0140-6736(54)92614-8

Cited by 46 publications

(19 citation statements)

References 11 publications

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“…Its mechanism is still unclear. Proposed theories include extension of inflammation to ocular nerves via sensory ramifications of V1 nerve,11 direct extension of the virus,12 microinfarction from occlusive vasculitis,13 chronic inflammatory cell infiltration of long posterior vessels and nerves14 and a demyelination process 15 16. HZO-induced ophthalmoplegia usually manifests 9–10 days after the onset of rash 17.…”

Section: Discussionmentioning

confidence: 99%

Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma

2013

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Many aetiologies have been associated with isolated oculomotor nerve palsies. They are ischaemic microangiopathy, posterior communicating artery aneurysm, uncal herniation, neoplasia, traumatic and inflammatory conditions. We report the case of a patient who presented with left oculomotor cranial nerve palsy with an associated large volume left acute on chronic subdural haematoma. Coincidentally, this woman was also found to have a recent history of herpes zoster ophthalmicus.

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Section: Discussionmentioning

confidence: 99%

Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma

2013

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“…HZ infections were first discovered to be associated with neurologic VZV vasculopathy in 1919, when it was described as a late contralateral hemiplegia following stroke (29) . Since then, there have been numerous reports of infarcts in the cerebrum, cerebellum, midbrain, and pons after HZ or varicella infection (30) .…”

Section: Vzv Vasculopathymentioning

confidence: 99%

Herpes zoster ophthalmicus and varicella zoster virus vasculopathy

Bandeira¹,

Roizenblatt²,

Levi³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopathy after adjusting for age, sex, body mass index, smoking, indicators of metabolic syndrome, and vascular and heart diseases. Considering the severity of this complication, vascular disease mediated by VZV requires early diagnosis and aggressive treatment. Finally, the anti-HZ vaccine has been recommended as a prophylactic measure in the elderly, but it should be used with caution in immunocompromised individuals.

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“…Three pathogenic mechanisms should be considered for mediating neural damage in zoster. The first is a direct cytopathic effect from the virus itself on the surrounding neural tissue (Cope and Jones, 1954). The second is an allergic response of the central nervous system to the virus, which is not primarily vascular (Krumholz and Luihan, 1945;Appelbaum et al, 1962;Rose et al, 1964).…”

Section: Pathogenesismentioning

confidence: 99%

“…A meningoencephalitis may develop (Schiff and Brain, 1930;Krumholz and Luihan, 1945;Worster-Drought and Sargent, 1949;Appelbaum et al, 1962;Rose et al, 1964;Norris et al, 1970). Contralateral hemiplegia occurs rarely, either in an isolated form (Baudouin and Lantvejoul, 1919;Rollett and Colrat, 1926;Biggart and Fisher, 1938;Hughes, 1951;Cope and Jones, 1954;Minton, 1956;Laws, 1960;Acers, 1964), or accompanied by hemianopia (Franceschetti et al, 1955), aphasia and agraphia (Gordon and Tucker, 1945;Leonardi, 1949;Anastostopoulos et al, 1958). Other cranial nerves may be implicated simultaneously.…”

mentioning

confidence: 99%

External ocular motor palsies in ophthalmic zoster: a review.

Marsh¹,

Dulley²,

Kelly³

1977

British Journal of Ophthalmology

109

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SUMMARY Seventy-seven new patients suffering from ophthalmic zoster and a selected group of 69 old patients were carefully examined with regard to external ocular movements. An incidence of 31 % of ocular pareses was found in the new patients, and 58 in all were analysed. We were surprised to find several of these were contralateral and bilateral palsies. 28 % of the palsies were asymptomatic, due to diplopia being present only in extremes of gaze and the rapid development of suppression in the affected eye. The theories of aetiology of these pareses are discussed.Herpes zoster ophthalmicus produces widely varying lesions of the eye in 500% of cases (Edgerton, 1945a)

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Hemiplegia Complicating Ophthalmic Zoster

Cited by 46 publications

References 11 publications

Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma

Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma

Herpes zoster ophthalmicus and varicella zoster virus vasculopathy

External ocular motor palsies in ophthalmic zoster: a review.

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