Hemilateral Distribution of Papular Lesions on the Buttock Histologically Resembling Granuloma Gluteale Infantum

Abstract

Two Japanese girls had small grouped papules on the buttocks without diaper dermatitis or bacterial or fungal infection. These granulomas spontaneously regressed over two weeks, even though oral antibiotics were administered. We discuss this variant of granuloma gluteale infantum of Tappeiner et al.

Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment

“…Clinically, granuloma gluteale infantum presents with asymptomatic, well-demarcated, firm, round-to-oval, red to purple, papules or nodules [1,11,14,15]. e size of lesions can range from 0.5 to 3 cm in diameter [11,[14][15][16]. e surface of the lesion can be smooth, lichenified, eroded, or ulcerated depending on the stage of lesions [1].…”

“…The surface of the lesion can be smooth, lichenified, eroded, or ulcerated depending on the stage of lesions [ 1 ]. Characteristically, the lesions occur on the convexities of the gluteal skin surfaces where there is maximum contact with the diaper and typically spare the inguinal folds [ 14 , 15 , 17 ] Postinflammatory hyperpigmentation and atrophic scars are potential complications, as illustrated in the present case [ 1 , 7 , 11 , 16 ].…”

A rare complication of diaper rash: Granuloma gluteale infantum

“…3 Histopathological examination of lesion results in neutrophils, lymphocytes, plasma cells, and dermal inflammatory perivascular infiltration high in eosinophils. 4 Rodriguez Cano L. and colleagues presented two GGI cases in 1994 who are followed-up under Hirschsprung diagnosis and who had developed perianal papuloid nodules. 5 Fungal elements may rarely accompany in some cases of GGI.…”

Erosive papulonodular dermatosis associated with topical benzocaine: A report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum

“…Other potential causative and/or exacerbating factors include Candida, fluorinated topical steroid use, starchcontaining powders, and plastic pants. [3][4][5]7,[22][23][24] In 1992, Goldberg et al 1 described a series of 5 children with an eruption in the perianal and suprapubic areas comprised of more than a dozen 2-to 8-mm shiny, smooth, red, moist, flat-topped, round lesions. All patients had either encopresis or urinary incontinence.…”

“…Occlusion, powder, topical halogenated steroids, Candida infection, urine, and feces are all postulated to contribute to the eruption. [3][4][5][6][7] Classically, the lesions appear as oval, red-purple, granulomatous nodules in areas of occlusion. Similar lesions may also be seen in adults.…”