Hemerocallis citrina Baroni ameliorates chronic sleep deprivation-induced cognitive deficits and depressive-like behaviours in mice

Jiang, Ning; Zhang, Yiwen; Yao, Caihong; Chen, Fang; Liu, Yupei; Chen, Yuzhen; Wang, Yan; Choudhary, Muhammad Iqbal; Liu, Xinmin

doi:10.1016/j.lssr.2023.04.001

Cited by 2 publications

(1 citation statement)

References 41 publications

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“…Since daylily flowers age quickly and can be predicted (after blooming, the daylily flower will wither within a day), they are usually steamed, dried, and processed into dried vegetables. In addition, daylily also has high medicinal value, with properties such as reducing inflammation [ 4 ], inhibiting cancer cell proliferation [ 5 ], improving sleep [ 6 , 7 ], resisting oxidation [ 2 , 8 ], and relieving depression [ 9 ], and has been used as a traditional medicine worldwide. In particular, daylily flower water extracts, mainly polysaccharides, have been included in the International Cosmetic Ingredient Dictionary and Handbook as a functional cosmetic ingredient.…”

Section: Introductionmentioning

confidence: 99%

A Novel Water-Soluble Polysaccharide from Daylily (Hemerocallis citrina Baroni): Isolation, Structure Analysis, and Probiotics Adhesion Promotion Effect

Ke,

Wang,

Xiao

et al. 2024

Foods

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The daylily (Hemerocallis citrina Baroni) flower is a traditional raw food material that is rich in a variety of nutrients. In particular, the content of polysaccharides in daylily is abundant and has been widely used as a functional component in food, cosmetics, medicine, and other industries. However, studies on the structure-effective relationship of daylily flower polysaccharides are still lacking. In view of this, daylily flower polysaccharides were isolated and purified, and their physical and chemical properties, structure, antioxidant activity, and adhesion-promoting effect on probiotics were evaluated. The results showed that a novel water-soluble polysaccharide (DPW) with an average molecular weight (Mw) of 2.224 kDa could be successfully isolated using column chromatography. Monosaccharide composition analysis showed that DPW only comprised glucose and fructose, with a molar ratio of 0.242:0.758. Through methylation and nuclear magnetic resonance (NMR) analysis, it was inferred that DPW belonged to the fructans group with a structure of α-D-Glcp-1→2-β-D-Fruf-1→(2-β-D-Fruf-1)n→. Antioxidant analysis showed that DPW showed strong 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-Oxide (PTIO-scavenging activity with IC50 of 1.54 mg/mL. DPW of 1.25 to 5 mg/mL could significantly increase the adhesion rate of Lactobacillus acidophilu, Lactobacillus casei, Bifidobacterium adolescentis, and Lactobacillus plantarum on Caco-2 cells. Considering the above results, the present study provides a theoretical basis and practical support for the development and application of daylily polysaccharides as a functional active ingredient.

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Section: Introductionmentioning

confidence: 99%

A Novel Water-Soluble Polysaccharide from Daylily (Hemerocallis citrina Baroni): Isolation, Structure Analysis, and Probiotics Adhesion Promotion Effect

Ke,

Wang,

Xiao

et al. 2024

Foods

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Salicylic acid modulates secondary metabolism and enhanced colchicine accumulation in long yellow daylily (Hemerocallis citrina)

Miao,

Li,

Pan

et al. 2024

AoB PLANTS

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Salicylic acid (SA) is an essential phytoregulator that is widely used to promote the synthesis of high-value nutraceuticals in plants. However, its application in daylily, an ornamental plant highly valued in traditional Chinese medicine, has not been reported. Herein, we investigated the exogenous SA-induced physiological, transcriptional, and biochemical changes in long yellow daylily (LYD). We found that 2 mg/L foliar SA treatment significantly improved LYD plant growth and yield. Transcriptome sequencing and differentially expressed genes analysis revealed that the phenylpropanoid biosynthesis, isoquinoline alkaloid biosynthesis, sulfur metabolism, plant hormone signal transduction, and tyrosine metabolism were significantly induced in SA-treated leaves. Many transcription factors and antioxidant system-related DEGs were induced under the SA treatment. Biochemical analyses showed that the leaf contents of soluble sugar (SS), soluble protein (Cpr), ascorbic acid (AsA), and colchicine were significantly increased by 15.15% (from 30.16±1.301 to 34.73±0.861 mg/g), 19.54% (from 60.3±2.227 to 72.08±1.617 mg/g), 30.45% (from 190.1±4.56 to 247.98±11.652 μg/g), and 73.05% (from 3.08±0.157 to 5.33±0.462 μg/g), respectively, under the SA treatment. Furthermore, we identified 15 potential candidate genes for enhancing the growth, production, and phytochemical content of LYD. Our results provide support for the bioaccumulation of colchicine in yellow daylily and valuable resources for biotechnological-assisted production of this important nutraceutical in Hemerocallis spp.

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Hemerocallis citrina Baroni ameliorates chronic sleep deprivation-induced cognitive deficits and depressive-like behaviours in mice

Cited by 2 publications

References 41 publications

A Novel Water-Soluble Polysaccharide from Daylily (Hemerocallis citrina Baroni): Isolation, Structure Analysis, and Probiotics Adhesion Promotion Effect

A Novel Water-Soluble Polysaccharide from Daylily (Hemerocallis citrina Baroni): Isolation, Structure Analysis, and Probiotics Adhesion Promotion Effect

Salicylic acid modulates secondary metabolism and enhanced colchicine accumulation in long yellow daylily (Hemerocallis citrina)

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