“…One of the first light responses at the cellular level is the translocation of photoactivated phys from the cytoplasm to the nucleus, where phys are further compartmentalized to subnuclear photosensory domains named photobodies (Sakamoto and Nagatani, 1996;Kircher et al, 1999;Yamaguchi et al, 1999;Chen et al, 2003Chen et al, , 2005Chen et al, , 2010Van Buskirk et al, 2012. A central mechanism by which phys control gene expression, possibly at photobodies, is by regulating the stability and activity of a group of nodal basic helix-loop-helix transcriptional regulators, the Phytochrome-Interacting Factors (PIFs; Shen et al, 2005;Al-Sady et al, 2006;Oh et al, 2006;Lorrain et al, 2008;Leivar and Quail, 2011;Park et al, 2012;Kaiserli et al, 2015;Qiu et al, 2015). Eight PIFs have been reported, including PIF1, PIF3-8, and PIL1 (PIF3-Like1), which perform overlapping and distinct antagonistic roles in photomorphogenesis (Ni et al, 1998;Huq and Quail, 2002;Huq et al, 2004;Khanna et al, 2004;Leivar et al, 2008a;Li et al, 2012;Luo et al, 2014).…”