Heme Oxygenase-1 and Prostate Cancer: Function, Regulation, and Implication in Cancer Therapy
Ramia J. Salloom,
Iman M. Ahmad,
Dania Z. Sahtout
et al.
Abstract:Prostate cancer (PC) is a significant cause of mortality in men worldwide, hence the need for a comprehensive understanding of the molecular mechanisms underlying its progression and resistance to treatment. Heme oxygenase-1 (HO-1), an inducible enzyme involved in heme catabolism, has emerged as a critical player in cancer biology, including PC. This review explores the multifaceted role of HO-1 in PC, encompassing its function, regulation, and implications in cancer therapy. HO-1 influences cell proliferation… Show more
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