Hematopoietic Stem Cell Development in Mammalian Embryos

Hou, Siyuan; Liu, Chen; Yao, Yingpeng; Bai, Zhijie; Gong, Yandong; Wang, Chaojie; He, Jian; You, Guoju; Zhang, Guangyu; Liu, Bing; Lan, Yu

doi:10.1007/978-981-99-7471-9_1

Advances in Experimental Medicine and Biology

2023

DOI: 10.1007/978-981-99-7471-9_1

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Hematopoietic Stem Cell Development in Mammalian Embryos

Siyuan Hou,

Chen Liu,

Yingpeng Yao

et al.

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2024

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Cited by 1 publication

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From Genesis to Old Age: Exploring the Immune System One Cell at a Time with Flow Cytometry

Larbi

2024

Biomedicines

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The immune system is a highly complex and tightly regulated system that plays a crucial role in protecting the body against external threats, such as pathogens, and internal abnormalities, like cancer cells. It undergoes development during fetal stages and continuously learns from each encounter with pathogens, allowing it to develop immunological memory and provide a wide range of immune protection. Over time, after numerous encounters and years of functioning, the immune system can begin to show signs of erosion, which is commonly named immunosenescence. In this review, we aim to explore how the immune system responds to initial encounters with antigens and how it handles persistent stimulations throughout a person’s lifetime. Our understanding of the immune system has greatly benefited from advanced technologies like flow cytometry. In this context, we will discuss the valuable contribution of flow cytometry in enhancing our knowledge of the immune system behavior in aging, with a specific focus on T-cells. Moreover, we will expand our discussion to the flow cytometry-based assessment of extracellular vesicles, a recently discovered communication channel in biology, and their implications for immune system functioning.

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From Genesis to Old Age: Exploring the Immune System One Cell at a Time with Flow Cytometry

Larbi

2024

Biomedicines

View full text Add to dashboard Cite

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Hematopoietic Stem Cell Development in Mammalian Embryos

Cited by 1 publication

References 141 publications

From Genesis to Old Age: Exploring the Immune System One Cell at a Time with Flow Cytometry

From Genesis to Old Age: Exploring the Immune System One Cell at a Time with Flow Cytometry

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