2022
DOI: 10.1016/j.bjps.2022.04.081
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Hematoma following gender-affirming mastectomy: A systematic review of the evidence

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Cited by 5 publications
(6 citation statements)
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“…21 Two frequent postoperative complications in patients undergoing gender-affirming mastectomy are seroma and hematoma, with the latter being the most common overall and the most common cause for return to the operating room. 3 Despite frequent use in other surgical specialties and increasing popularity within plastic surgery, 18,19 this study represents the first to evaluate the effect of TXA among patients undergoing gender-affirming mastectomy. Our results demonstrated significantly reduced rates of both hematoma and seroma in patients who received intravenous TXA without increased rates of VTE or other adverse events.…”
Section: Discussionmentioning
confidence: 98%
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“…21 Two frequent postoperative complications in patients undergoing gender-affirming mastectomy are seroma and hematoma, with the latter being the most common overall and the most common cause for return to the operating room. 3 Despite frequent use in other surgical specialties and increasing popularity within plastic surgery, 18,19 this study represents the first to evaluate the effect of TXA among patients undergoing gender-affirming mastectomy. Our results demonstrated significantly reduced rates of both hematoma and seroma in patients who received intravenous TXA without increased rates of VTE or other adverse events.…”
Section: Discussionmentioning
confidence: 98%
“…1,2 Postoperative seroma and hematoma are two common complications of gender-affirming mastectomy, with the latter being the most frequently reported, occurring in up to 31.2% of patients, which is substantially higher than in other types of breast surgery. 3…”
mentioning
confidence: 99%
“…1,14,15 In addition, a large systematic review demonstrated there is no association between usage of testosterone and hematoma in gender-affirming mastectomy. 16 Rather, the strongest risk factor of developing a hematoma is due to the surgical technique of limited incision such as periareolar or circumareolar approaches. 16 A recently published study comparing complication profiles in patients who discontinued testosterone versus patients who maintained on HRT found that there was no difference in postoperative complication rates including hematoma, seroma, VTE, and overall complications.…”
Section: Discussionmentioning
confidence: 99%
“…16 Rather, the strongest risk factor of developing a hematoma is due to the surgical technique of limited incision such as periareolar or circumareolar approaches. 16 A recently published study comparing complication profiles in patients who discontinued testosterone versus patients who maintained on HRT found that there was no difference in postoperative complication rates including hematoma, seroma, VTE, and overall complications. 17 Boskey et al 4 synthesized all the surgical risks of exogenous hormones in transgender and gender-diverse patients and concluded that the current evidence does not support routine discontinuation of HRT before GAS.…”
Section: Discussionmentioning
confidence: 99%
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