Hematology and Immune-Related Disorders

Javinsky, Edward

doi:10.1016/b978-1-4377-0660-4.00025-9

Cited by 5 publications

(3 citation statements)

References 77 publications

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“…Kematian diduga disebabkan oleh anemia akibat hemolisis yang terjadi pada kucing kasus. Hemolisis yang parah dapat menyebabkan terjadinya hipoksia dan memperburuk kerusakan pada organ (Javinsky, 2012).…”

Section: Pembahasanunclassified

Jaundice akibat Hepatic Lipidosis dan Feline Immunodeficiency Virus pada Kucing

Listiana Dewi,

Suartha,

Erawan

2023

bulvet

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Feline Immunodeficiency Virus (FIV) merupakan salah satu penyakit yang disebabkan oleh virus yang menyerang system kekebalan tubuh kucing. Feline Hepatic Lipidosis (FHL) merupakan penyakit hati yang paling umum pada kucing yang disebabkan oleh akumulasi trigliserida yang berlebihan di dalam hepatosit yang menyebabkan kolestasis dan disfungsi hati. Studi kasus ini bertujuan untuk mengetahui cara mendiagnosis dan penanganan kasus penyebab jaundice pada kucing. Seekor kucing Himalaya berumur 7 tahun bobot badan 3,3 kg diperiksa di Klinik Listriani Vetcare dalam kondisi lemas. Sebelumnya kucing tersebut hilang selama 50 hari dan kemudian ditemukan di gudang tetangga yang hanya terdapat rembesan air hujan. Pada pemeriksaan fisik ditemukan adanya jaundice pada telinga, sclera, bibir, dan abdomen, serta teramati adanya distensi abdomen. Dilakukan pemeriksaan hematologi dua kali pada hari ke-2 dan hari ke-9, kimia darah, ultrasonografi, dan test kit FIV/FelV. Pemeriksaan hematologi hari ke-2 menunjukkan kucing kasus mengalami anemia ringan, leukopenia, neutropenia, dan trombositopenia. Pemeriksaan hematologi hari ke-9 menunjukkan anemia, neutrofilia, dan trombositopenia. Hasil kimia darah menunjukkan peningkatan pada alkaline phospatase, alanine aminotransferase, gamma-glutamyl transferase, total bilirubin, asam empedu, total kolesterol, dan penurunan pada Blood Urea Nitrogen. Ultrasonografi hati menunjukkan adanya massa hyperechoic difus dan test kit FIV/FelV menunjukkan positif FIV. Berdasarkan anamnesis, pemeriksaan klinis, dan uji laboratorium kucing kasus didiagnosis menderita hepatic lipidosis dan FIV dengan prognosis dubius. Kucing kasus diterapi dengan Cefotaxime (20 mg/kg BB, IV, tiga kali sehari), Hematodin® (0,6 mL, IV, satu kali sehari), Ondansetron (0,2 mg/kg BB, IV, dua kali sehari), Samylin® small (1 tab, satu kali sehari), Metronidazole (25 mg/kg BB, PO, dua kali sehari) selama 10 hari, Urdafalk (15 mg/kg BB, PO, satu kali sehari), Lactulose® (3 mL, PO, tiga kali sehari). Pada hari ke-5, pemberian ondansetron dan cefotaxime dihentikan dan diberikan Cephalexin (38 mg/kg BB, PO, dua kali sehari), Iron (1 tab, PO satu kali sehari), vitamin B12 (0,2 mL IV) dan TF Advance® (1 kapsul, dua kali sehari). Pengobatan yang diberikan tidak memperbaiki kondisi, kucing kasus mati pada hari ke-13. Disarankan agar pemilik tidak memberikan akses untuk kucing keluar rumah untuk mengurangi kemungkinan kucing hilang atau kontak dengan kucing lain yang dapat menularkan penyakit.

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Section: Pembahasanunclassified

Jaundice akibat Hepatic Lipidosis dan Feline Immunodeficiency Virus pada Kucing

Listiana Dewi,

Suartha,

Erawan

2023

bulvet

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“…The third species of hemoplasm in cats was found by Willi et al In 2005 and designated Candidatus M. turicensis (Sykes, 2010) and these mycoplasmas that have 'Candidatus' to their nomenclature are recent and with unfinished characterization (Messick, 2004). (Javinky et al 2012). The most pathogenic is M. haemofelis, which is mainly related to hemolytic anemia (Stockham e Scott, 2012).The mycoplasmas present the peculiarity of not being able to be cultured in vitro, the infecting dose can not be established with experimental accuracy interfering in the results (Carneiro, 2015).…”

Section: Being Namedmentioning

confidence: 99%

Molecular detection of Mycoplasma haemofelis in domestic cats from municipality of mineiros, Goiás

Silva¹,

Borges²,

Cândido

et al. 2020

BJD

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Feline mycoplasmosis is caused by Mycoplasma haemofelis agent and your transmission is through the sanguine meal of ectoparasitas, due the lack of studies on the disease is considered serious and of difficult diagnnosis being more necessary studies in order to explain the transmission, patogenia and control. This work had as objective analyzed animals of Mineiros-GO and to verify possible the existence of this microorganism, where all the tested felines obtained negative result through the technique of Polimerase chain reaction (PCR).

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“…Feline Hgb has a lower affinity to oxygen (and is more readily uptaked by tissues) [ 26 ], resulting in a lower packed cell volume (PCV) and Hgb concentration than in canines [ 39 ]. Feline PLT are larger and exhibit greater size variation (15 to 18

m) in comparison to other domestic mammals [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

Reagentless Vis-NIR Spectroscopy Point-of-Care for Feline Total White Blood Cell Counts

Barroso,

Queirós,

Monteiro-Silva

et al. 2024

Biosensors

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Spectral point-of-care technology is reagentless with minimal sampling (<10 μL) and can be performed in real-time. White blood cells are non-dominant in blood and in spectral information, suffering significant interferences from dominant constituents such as red blood cells, hemoglobin and billirubin. White blood cells of a bigger size can account for 0.5% to 22.5% of blood spectra information. Knowledge expansion was performed using data augmentation through the hybridization of 94 real-world blood samples into 300 synthetic data samples. Synthetic data samples are representative of real-world data, expanding the detailed spectral information through sample hybridization, allowing us to unscramble the spectral white blood cell information from spectra, with correlations of 0.7975 to 0.8397 and a mean absolute error of 32.25% to 34.13%; furthermore, we achieved a diagnostic efficiency between 83% and 100% inside the reference interval (5.5 to 19.5 × 109 cell/L), and 85.11% for cases with extreme high white blood cell counts. At the covariance mode level, white blood cells are quantified using orthogonal information on red blood cells, maximizing sensitivity and specificity towards white blood cells, and avoiding the use of non-specific natural correlations present in the dataset; thus, the specifity of white blood cells spectral information is increased. The presented research is a step towards high-specificity, reagentless, miniaturized spectral point-of-care hematology technology for Veterinary Medicine.

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Hematology and Immune-Related Disorders

Cited by 5 publications

References 77 publications

Jaundice akibat Hepatic Lipidosis dan Feline Immunodeficiency Virus pada Kucing

Jaundice akibat Hepatic Lipidosis dan Feline Immunodeficiency Virus pada Kucing

Molecular detection of Mycoplasma haemofelis in domestic cats from municipality of mineiros, Goiás

Reagentless Vis-NIR Spectroscopy Point-of-Care for Feline Total White Blood Cell Counts

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