Hematological parameters in patients with acnes

Chen, Tingqiao; Chen, Yangmei; Shao, Xinyi; Chen, Jiayi; Liu, Lin; Li, Yuxin; Pu, Yihuan; Chen, Jin

doi:10.1111/jocd.15676

Cited by 5 publications

(1 citation statement)

References 24 publications

(44 reference statements)

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“…Studies examining the NLR in AV also appear in the literature. One such study determined no significant relationship was found between NLR and severity of AV [ 11 ]. In contrast, another study reported higher NLR values in patients with AV than in a control group [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Relationships Between Disease Severity and the C-reactive Protein/Albumin Ratio and Various Hematological Parameters in Patients With Acne Vulgaris

Pala,

Bayraktar

2023

Cureus

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Objective: Acne vulgaris, an inflammatory disease, was investigated in this study with the claim that the C-reactive protein (CRP)/albumin ratio and some hematological parameter ratios have the potential to be used as inflammatory markers to monitor disease severity and prognosis. Methods: A descriptive cross-sectional study was conducted with two groups of patients aged 18-65 years, 61 patients diagnosed with acne vulgaris and 35 healthy control patients, and routine hemogram and biochemical parameters were compared. The Global Acne Severity Index was used to determine the severity of acne vulgaris. Results: The median age of acne patients was 22.0 (IQR=5.0) and the median age of healthy volunteers was 30.0 (IQR=14.0). There were 75.4% (n=46) women in the acne group and 77.1% (n=27) women in the control group. Among the acne patients, 42.6% (n=26) had mild acne, and 41% (n=25) had moderate acne severity. A significant difference was found between the study groups in terms of CRP/albumin ratio, CRP, monocyte/lymphocyte ratio (MLR), lymphocyte/albumin ratio (LAR), and monocyte/CRP ratio (MCR) according to laboratory test results and calculated test ratios (p<0.05). The area under the curve (AUC) value of the CRP/albumin ratio in the receiver operating characteristic (ROC) analysis between the acne and control groups was 0.660, and its cut-off value was found to be 0.236 with 68.6% sensitivity and 68.9% specificity. Conclusion: This study is the first to compare the CRP/albumin ratio with the severity of acne vulgaris in the literature. CRP/albumin ratio and MCR may serve as inflammatory markers that can be used to monitor the severity of acne vulgaris.

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Section: Discussionmentioning

confidence: 99%

Relationships Between Disease Severity and the C-reactive Protein/Albumin Ratio and Various Hematological Parameters in Patients With Acne Vulgaris

Pala,

Bayraktar

2023

Cureus

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Relationship between circulating white blood cell count and inflammatory skin disease: a bidirectional mendelian randomization study

Yuan,

Che,

Wang

et al. 2024

Arch Dermatol Res

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The Association of Acne Severity with Inflammatory and Metabolic Markers: A Prospective Cross-sectional Study

METİN,

TUR,

AKOGUL

et al. 2023

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

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Amaç: Bu çalışmada inflamatuar ve metabolik belirteçlerin akne şiddeti ve birbirleri ile olan ilişkilerini incelemek, bu belirteçlerin akne mekanizmasındaki farklı inflamatuar ve metabolik yollardaki etkinliklerini bir bütün olarak araştırmak amaçlanmıştır. Gereç ve Yöntemler: Çalışmamız akne tanısı almış 203 hasta ile prospektif kesitsel bir çalışma olarak yürütüldü. Akne şiddeti “International Consensus Conference on Acne Classification System” ’e göre hafif, orta ve ağır olarak üç sınıfa ayrıldı. Hastaların inflamatuar ve metabolik belirteçlerinden fibrinojen/albümin oranı (FAO), D-dimer/albümin oranı (DAO), ürik asit/HDL oranı (UHO), CRP, sedimantasyon (ESH), lökosit sayısı (WBC), D-vitamini, trigliserid (TG) ve HOMA-IR değerlerine bakıldı. Elde edilen değerlerin akne şiddeti ve birbirleri ile ilişkileri incelendi. İstatiksel test olarak Mann- Whitney U testi, Kruskal-Wallis H testi ve Spearmans korelasyon analizinden faydalanıldı. Bulgular: Çalışmamızda CRP (p=0.008), WBC (p=0.006) ve yeni inflamatuar belirteçlerden UHO’nun (p

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Hematological parameters in patients with acnes

Cited by 5 publications

References 24 publications

Relationships Between Disease Severity and the C-reactive Protein/Albumin Ratio and Various Hematological Parameters in Patients With Acne Vulgaris

Relationships Between Disease Severity and the C-reactive Protein/Albumin Ratio and Various Hematological Parameters in Patients With Acne Vulgaris

Relationship between circulating white blood cell count and inflammatory skin disease: a bidirectional mendelian randomization study

The Association of Acne Severity with Inflammatory and Metabolic Markers: A Prospective Cross-sectional Study

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