Hematological Aspects on Dogs with Apparent Dysbiosis after Bacillus Subtilis, Bacillus Licheniformis and Pediococcus Acidilactici Probiotic Administration- Pilot Study

Abstract

The aim of the study was to assess the effect of a probiotic product based on Bacillus subtilis, Bacillus licheniformis and Pediococcus acidilactici on hematological parameters for dogs with apparent intestinal dysbiosis. Also, a comparison between the results obtained before and after the treatment was made, in order to establish if the probiotic treatment is able to improve the hematological results for dogs with apparent dysbiosis. A total number of 5 dogs, aged between 7 months and 6 years old were clinically evaluated for gastro-intestinal problems that lead to the suspicion of apparent intestinal dysbiosis. The probiotic administration respected the producer recommendations and it was given to the dogs together with their usual food, one capsule/day, 30 days consecutively. On the first and 31 days of the study, blood samples were collected and hematological parameters were evaluated. A heterogeneity in the hematological results was observed. However, when results from day 0 were compared with results obtained in day 31, the variance was considered to be physiological. Also, the small diferences between the values before and after the treatment can not be attributed only to the probiotic treatment. The results obtained regarding the dynamics of the hematological parameters provided data that sustain the benefic effect of this probiotic combination, without a direct impact on hematological parameters.

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“…Furthermore, disturbances in gut microbiota composition, often referred to as dysbiosis, can lead to an imbalance in metabolite production. Dysbiosis may result from factors like dietary habits, medications, physical activity, and underlying health conditions, further impacting kidney function and disease progression [64,65]. Nonetheless, both vegetarian and omnivore diets have their advantages and challenges when it comes to their impact on kidney affections, such as uremia and CKD [66].…”

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