Hematologic Cancer Survivorship Management: Transplantation

Stolar, Karen; Alousi, Amin M.; Neumann, Joyce; Champlin, Richard E.

doi:10.1007/978-1-4939-0986-5_10

Cited by 1 publication

(1 citation statement)

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“…In addition, hematologic cancer patients receive repetitive chemotherapy, with multiple agents and hematopoietic stem cell transplantation with immunosuppressive therapy [5,6]. This makes patients more vulnerable to opportunistic infections, cardiopulmonary deconditioning, and nutritional deficiencies [7]. Fatigue and pain also contributed, to reducing motivation for rehabilitation.…”

Section: Introductionmentioning

confidence: 99%

Effect of an Inpatient Rehabilitation Program for Recovery of Deconditioning in Hematologic Cancer Patients After Chemotherapy

Cha¹,

Kim²,

Lee³

et al. 2018

Ann Rehabil Med

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ObjectiveTo investigate the effect of a rehabilitation program in terms of De Morton Mobility Index (DEMMI) score, in hematologic cancer patients after chemotherapy.MethodsHematologic cancer patients admitted for chemotherapy were reviewed. They received a rehabilitation program during their hospital stay. DEMMI score measurement was performed, before and after rehabilitation. Demographics, diagnosis, chemotherapy information, rehabilitation program duration, mortality, body mass index (BMI), and laboratory test results were collected. For analysis, patients were classified according to diagnosis (multiple myeloma, leukemia, and others), mortality, and additional chemotherapy.ResultsThere was statistically significant improvement in DEMMI score of 10.1 points (95% confidence interval, 5.9–14.3) after rehabilitation. It was more evident in the multiple myeloma group, and they revealed less mortality. When patients were divided according to mortality, survivors received the program earlier, and in a shorter period than in mortality cases. Although survivors revealed higher initial DEMMI score, improvement after rehabilitation did not differ significantly.ConclusionIn hematologic cancer patients, rehabilitation program was effective for recovery from deconditioning, revealing significant increase in DEMMI score. Multiple myeloma patients may be good candidates for rehabilitation. Rehabilitation could be sustained during chemotherapy and for high-risk patients.

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Section: Introductionmentioning

confidence: 99%