Hemangiopericytoma of the thoracic spine: a case report

Abstract

Hemangiopericytoma (HPC) has been described to be aggressive and potentially a malignant tumour. We report a rare case of a 63-year-old Chinese male who presented with primary intradural extramedullary HPC of the thoracic spine. The main presenting complaint was gradual progression of back pain, associated with paraparesis and sensory deficit of lower limbs. He had MRI thoracolumbar with contrast which showed T9 lesion compressing on spinal cord and oedema, he was then operated upon and histopathology report confirmed a thoracic spine HPC. A T8/9 laminectomy and excision of intradural extramedullary lesion was performed, tumour section was sent for frozen section study, and more tissue was sent for paraffin studies and additional immunohistochemical staining. Surgical resection is most commonly performed, radiotherapy remains debatable. In this report, we discussed another rare case of primary spinal HPC to be added into the literature.

Spinal location is prognostic of survival for solitary-fibrous tumor/hemangiopericytoma of the central nervous system

“…Few studies have presented a combined analysis of SFT/HPC since the WHO guidelines were updated in 2016 [1], in part due to the rarity of these tumors [14,42,43]. Those that have report conflicting results [7,9,14,18,19] with regards to classification, optimal management, and outcome.…”

A Rare Case of a Thoracic Spinal Hemangiopericytoma

“…The 2016 WHO classification considers hemangiopericytomas and solitary fibrotic tumors of the nervous system as the same pathological entity due to immunohistochemical and molecular lesional similarities [3]. The primary spinal location of hemangiopericytomas has been rarely reported in the literature [2]. To date, about 80 cases of spinal hemangiopericytomas have been reported and the cervico-dorsal spine is the most frequent site [1].…”

“…The case we report had rather a homogeneous enhancement with T1 contrast MRI and no T2 void signal. The differential radiological diagnosis of spinal hemangiopericytomas is mainly dis-Open Journal of Modern Neurosurgery cussed with meningiomas, schwannomas, neurofibromas and neuroblastomas [2]. The lack of specificity of the clinical and radiological manifestations makes the diagnosis unclear.…”

“…The hemangiopericytoma is a rare and malignant tumor of the central nervous system classically developed from the meninges and able to metastasize outside the neuraxis [1]. It represents less than 1% of all the central nervous system tumors and 2% of the primary meningeal tumors [2]. Hemangiopericytomas have been first considered to be angioblastic meningiomas before OMS classified them as non-meningothelial tumors of mesenchymal origin in 1993 [1].…”

Intracranial myopericytoma: a tumour in a rare location

“…After that, only two more articles make reference to intracranial myopericytomas—Zhang et al 5 and Holling et al ,6 the latter with reference to a cohort of five patients, where the authors include also one peripheral nervous system and two intraspinal myopericytoma; intraspinal location has also been reported in the past by Cox and Giltman,7 Hunald et al ,8 Agrawal and Nag,9 Brunschweiler et al ,10 Chew et al 11 and by Cobos I and Hedley-Whyte ET (personal communication, 2014).…”