Hemangiopericytoma-like synovial sarcoma of the lumbar spine

Sakellaridis, Nikolaos; Mahera, H; Pomonis, Spiros

doi:10.3171/spi.2006.4.2.179

Cited by 22 publications

(17 citation statements)

References 27 publications

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“…Paravertebral site is the most common region for SS in the head and neck, with the presentaion from skull base to the hypopharynx (including pharyngeal, parapharyngeal, and the prevertebral planes; skull base and temporomandibular joint fossa) (Tilakaratneet al, 2006;Horbinsk et al, 2008;Al-Daraji et al, 2009;Scheithaueret al, 2011;Keith et al, 2013;Lin et al, 2013;Xiao et al, 2014). Occurences besides extremities or head and neck have also been documented, such as thorax (including heart and lungs), even rarely within abdomen and pelvis (Witkin et al, 1989;Gaertner et al, 1996;Nicholson et al, 1997;Nicholson et al, 1998;Fisher et al, 2004;Suster et al, 2005;Sakellaridis et al, 2006;Company et al, 2007;Schreiberet al, 2007;Makhlouf et al, 2008;Katakura et al, 2009;Cummings et al, 2010;Alsharief et al, 2012;Dhawan et al, 2012Nomura et al, 2014Crowson et al, 2015;Eravci et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

Intraventricular Synovial Sarcoma: A Case Report and Literature Review

Dou¹,

Zhang²

2017

cge

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Synovial sarcoma (SS) is a high-grade malignant neoplasm. SS is a rare cancer type, which is primarily derived from the soft tissues of the lower extremities. The head and neck region is quite an extremely rare location, particularly the ventricle.The origin of SS remains a challenge, which along with its propensity to present clinical features mimicking other neoplasms within the common site, can result in significant diagnostic difficulty.Herein, we present a case of 40-year-old male SS located in the left ventricle with information including manifestation, imaging and histopathological features.On CT, approximately 30% of cases appear detectable calcification, which may be focal or dispersed throughout the tumor, often with a fine, stippled, or opaque appearance. MRI revealed a heterogeneous expansive and multi-lobular mass involving left ventricle, with intense and heterogeneous enhancement. Tentorium was thickened and enhanced. Small cystic changes were found in the peripheral part of the tumor with no enhancement. . Radiologically, discriminating SS from other types of cancer is very difficult. Nonetheless, they should be considered in the differential diagnosis. Owing to the rarity of SS in the ventricle, misdiagnosis is commonIn summary, we report one SS in the ventricle, the unusual location, to remind the radiologist to make it come to our mind for future work.

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Section: Discussionmentioning

confidence: 99%

Intraventricular Synovial Sarcoma: A Case Report and Literature Review

Dou¹,

Zhang²

2017

cge

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“…The incidence of SS is 2.75 per 100,000 individuals [6]. It is the disease of adolescents and young adults, the mean age of diagnoses being 35.4 years [7].…”

Section: Discussionmentioning

confidence: 99%

“…In absolute terms, the SS of the lungs and the pleura are extremely rare [6,7], and pose a diagnostic difficulty. Review of literature shows only few case reports and small case series that report tumours of similar lineage [1,[11][12][13].…”

Section: Discussionmentioning

confidence: 99%

Primary Pleuropulmonary Synovial Sarcoma with Brain Metastases in a Paediatric Patient: An Unusual Presentation

Chirmade

Parikh

Anand

et al. 2017

Advances in Respiratory Medicine

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Primary lung neoplasms are rare in children. The most common primary lung malignancies in children are pleuropulmonary blastoma and carcinoid tumour. Synovial sarcoma (SS) accounts for approximately 1% of all childhood malignancies. In absolute terms, the SS of the lungs and pleura are extremely rare and pose a diagnostic difficulty. Soft tissue sarcomas usually have a high potential for metastases, however, metastasis to the brain is rare, even in widely disseminated disease, and it has been described only in 3 case reports previously. Primary pleuropulmonary SS with brain metastases is even rarer. Here we present a case of an 11-year-old boy who presented with respiratory complaints, viz. fever and cough for 20 days. Initial impression was lung abscess, however, on histopathological, immunohistochemical and molecular study, the disorder was diagnosed as synovial sarcoma. After a week from the first consult, the child developed neurological symptoms, viz., an episode of convulsion and gradually worsening power of the lower limb. Computed tomography scan and Magnetic Resonance Spectroscopy was suggestive of brain metastases. Given the rarity of primary lung neoplasms in children, clinical detection remains a challenge. Delayed diagnoses are common as respiratory symptoms may be attributed to inflammatory or infective processes. Primary pleuropulmonary synovial sarcoma is a rare tumour and it is not known to commonly metastasise to the brain. Though rare, primary pleuropulmonary SS should be considered an important differential among peadiatric primary lung neoplasms due to its potential for curability if detected early, and more aggressive metastatic pattern, e.g. brain metastases making early detection imperative.

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“…The vast majority of primary synovial sarcomas metastasize to the lungs (1,2). Metastases occur in approximately half of all cases of synovial sarcomas (1,4,8), with a resultant 5-year disease-specific mortality of 37% (8). The sites most affected by metastases are the lung, lymph nodes, and bone marrow (4).…”

Section: Case Reportmentioning

confidence: 99%

Metastatic Synovial Sarcoma With Cervical Spinal Cord Compression Treated With Posterior Ventral Resection: Case Report

Arnold

Roh

et al. 2010

The Journal of Spinal Cord Medicine

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Context: Synovial sarcomas, which represent 5% to 10% of all adult soft-tissue sarcomas, usually metastasize to the lungs. Metastasis to the spine is rare. Spinal cord compression due to spinal metastasis occurs in approximately 3% of patients with extraspinal soft-tissue sarcomas. Method: Case report. Findings: A 26-year-old woman presented with neck pain, arm weakness, and a history of metastatic synovial sarcoma originating at the right knee. Computed tomography revealed destruction of the odontoid and C2 body. Magnetic resonance imaging revealed tumor in the posterior elements of C2 and in the ventral epidural space from C2-C5. She was treated with C2-C3 laminectomy, posterior C2 corpectomy with occipital-C7 fixation, and fusion. Postoperatively, her neck pain resolved and left upper extremity strength returned to normal. Conclusion and Clinical Relevance: Metastatic spinal cord compression from synovial sarcoma is rare. Surgical resection can lead to neurologic improvement.

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Hemangiopericytoma-like synovial sarcoma of the lumbar spine

Cited by 22 publications

References 27 publications

Intraventricular Synovial Sarcoma: A Case Report and Literature Review

Intraventricular Synovial Sarcoma: A Case Report and Literature Review

Primary Pleuropulmonary Synovial Sarcoma with Brain Metastases in a Paediatric Patient: An Unusual Presentation

Metastatic Synovial Sarcoma With Cervical Spinal Cord Compression Treated With Posterior Ventral Resection: Case Report

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