Hemangiomatous neck plaques in a child with cleft lip

Bilateral second branchial cleft fistulae coexisting with bilateral cleft lip and bilateral supra‐auricular fissures

“…Facial abnormalities and skin lesions are characteristics of BOFS. 3,4 Branchial arch anomalies may present with sinus tracts or aplastic skin in the cervical area, supra-auricular sinuses or branchial clefts with hemangiomatous scarred skin extending along the sternocleidomastoid muscle like in our patient. 3 The opposite skin may be thin or present hair patches, or linear, and non-healing erosions.…”

“…Otherwise, two of these criteria plus either an affected first-degree relative or dermal ectopic thymus made the diagnosis. 4 A differential diagnosis includes branchio-otorenal (BOR) syndrome. Both the BOR and BOFS can present with hearing loss, renal anomalies, and nasolacrimal stenosis.…”

“…3 The opposite skin may be thin or present hair patches, or linear, and non-healing erosions. 4 The face may manifest dolichocephaly, a malformed, asymmetrical nose with a broad bridge and flattened lip, low set ears with posterior rotation, cleft palate and/or cleft lip.…”

“…The last three findings were present in our case. 4 Microphthalmia or anophthalmia, strabismus, nasolacrimal duct stenosis or atresia with recurrent dacrocystitis and cataracts represent ocular abnormalities in BOFS. 3 Our patient underwent surgical treatment under general anesthesia.…”