Hemangioendothelioma of the Spine

Aflatoon, Kamran; Staals, Eric L.; Bertoni, Franco; Bacchini, Patrizia; Donati, Davide María; Fabbri, Nicola; Boriani, S.; Frassica, Frank J.

doi:10.1097/00003086-200401000-00031

Cited by 27 publications

(27 citation statements)

References 16 publications

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“…In three large case series, all patients presented with local neck or back pain (1,5,14). Pathological fractures associated with back pain have also been described as a common presentation.…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Luzzati et al (14) reported pathological fracture in eight out of ten cases in their series. Soft-tissue extensions can lead to neurologic compression, which result in neurologic symptoms such as paresthesia, weakness, and paraplegia (1,5,7,8,15,29,(32)(33)(34)36,(41)(42)(43)(44)(45).…”

Section: Clinical Presentationmentioning

confidence: 99%

“…According to few reports in literatures, radiotherapy for spinal EHE is used in partially excised lesions and when it is difficult to access the lesion (5,16,43,46). Campanacci et al recommended the use of postoperative radiotherapy to decrease the risk of local recurrence after surgery (48).…”

Section: Treatmentmentioning

confidence: 99%

“…These tumors can be asymptomatic and discovered as an incidental finding. However, local pain is the most common presentation of spinal EHE (5).…”

Section: Introductionmentioning

confidence: 99%

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Epithelioid hemangioendothelioma of the spine: case report and review of the literature

Albakr¹,

Schell²,

Drew³

et al. 2017

J. Spine Surg.

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Epithelioid hemangioendothelioma (EHE) has been described as a rare vascular bone lesion with histological features between hemangioma and high-grade angiosarcoma. Spinal EHE is a quite rare disease with few case reports and series reported in the literature. The tumor cells are positive for vimentin, CD31and The patient was started on local radiation therapy (RT). On follow-up, 3 months after the second surgery, the thoracic spinal pain had improved dramatically. Our review highlights the diagnosis, clinical presentation, and treatment of spinal EHE. Complete resection is associated with good outcome. Radiotherapy has been used in partially resected lesions. However, the role of radiotherapy as primary treatment is not yet defined.Further studies should develop a treatment algorithm for this rare tumour.

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Section: Clinical Presentationmentioning

confidence: 99%

Section: Clinical Presentationmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

“…These tumors can be asymptomatic and discovered as an incidental finding. However, local pain is the most common presentation of spinal EHE (5).…”

Section: Introductionmentioning

confidence: 99%

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Epithelioid hemangioendothelioma of the spine: case report and review of the literature

Albakr¹,

Schell²,

Drew³

et al. 2017

J. Spine Surg.

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“…One such type is hemangioendothelioma, an intermediate-grade tumor that displays a more aggressive clinical course compared with hemangiomas, but is less malignant than angiosarcomas. 2 The 3 histological subtypes of hemangioendotheliomas include epithelioid hemangioendothelioma, spindle cell hemangioendothelioma, and malignant endovascular papillary angioendothelioma. 26 Spindle cell hemangioendothelioma is a subtype initially described by Weiss and Enzinger 25 as a low-grade vascular neoplasm with features of both hemangioma and Kaposi sarcoma.…”

mentioning

confidence: 99%

Spindle cell hemangioendothelioma of the sacrum

Winter

Siu²,

Jamshidi

et al. 2014

SPI

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Spindle cell hemangioendothelioma is a rare benign vascular tumor that is not known to involve the sacrum. The authors describe the case of a 31-year-old woman presenting with low-back and radicular pain without weakness or bowel or bladder dysfunction. Admission CT and MRI studies revealed a large S1–3 lytic sacral lesion. The patient initially underwent a nondiagnostic percutaneous biopsy. She subsequently underwent an open biopsy, during which the lesion was found to be highly vascular. Histological investigation revealed a vasoformative lesion consistent with spindle cell hemangioendothelioma. Preoperative embolization followed by resection via intralesional currettage resulted in resolution of symptoms up to 9 months postintervention. Despite the authors' recommendation, the patient became pregnant at that time and requested no additional follow-up imaging. The authors present the first reported case of a spindle cell hemangioendothelioma of the sacrum and review the current literature.

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