HEMA-Lysine-Based Cryogels for Highly Selective Heparin Neutralization
Tommaso Mecca,
Fabiola Spitaleri,
Rita La Spina
et al.
Abstract:Unfractionated heparin (UFH) and its low-molecular-weight fragments (LMWH) are widely used as anticoagulants for surgical procedures and extracorporeal blood purification therapies such as cardiovascular surgery and dialysis. The anticoagulant effect of heparin is essential for the optimal execution of extracorporeal blood circulation. However, at the end of these procedures, to avoid the risk of bleeding, it is necessary to neutralize it. Currently, the only antidote for heparin neutralization is protamine su… Show more
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