Helminth infections and risk factor analysis among residents in Eryuan county, Yunnan province, China

Steinmann, Peter; Zhou, Xiao‐Nong; YuanLin, Li; Liu, Hongjun; Chen, Shao-rong; Yang, Zhong; Fan, Weiliang; Jia, Ting; Li, Lanhua; Vounatsou, Penelope; Utzinger, J

doi:10.1016/j.actatropica.2007.07.003

Cited by 70 publications

(73 citation statements)

References 29 publications

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“…Our data underscore that multiparasitism is very common in Lao PDR and these findings support observations from neighbouring countries such as Vietnam [25][26][27] and from other parts of the developing world. 21,22,[28][29][30] Hence, our results and those from other groups who worked in Lao PDR 7,8 call for concerted action to remedy the issue of multiparasitism. Of particular public health relevance are our results in relation to the diversity of trematodes identified.…”

Section: Discussionsupporting

confidence: 53%

“…Previous studies have shown that multiple Kato-Katz thick smears plus other diagnostic methods are mandatory to achieve a high diagnostic sensitivity. [21][22][23] In the present study, only 15 individuals (6.5%) were diagnosed as free of any intestinal parasite. It is conceivable that the actual number of parasite-free individuals is even lower, as some light infections might have been missed despite the rigorous diagnostic approach.…”

Section: Discussioncontrasting

confidence: 53%

“…Repeated stool examinations have been shown to improve significantly the diagnostic accuracy for parasitic infections. 22,24,[36][37][38] It follows that FECT performed on multiple stool samples holds promise for accurate and species-specific diagnosis. However, such an approach is time consuming and is likely to compromise compliance, as study participants are reluctant to provide multiple stool specimens.…”

Section: Discussionmentioning

confidence: 99%

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Diversity of human intestinal helminthiasis in Lao PDR

Sayasone

Vonghajack

Vanmany

et al. 2009

Transactions of the Royal Society of Tropical Medicine and Hygi

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109

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Summary Food-borne trematodiasis is an emerging public health problem, including in Lao PDR. We investigated the diversity of intestinal helminthes and polyparasitism in patients with hepatobiliary or intestinal symptoms in hospital and community-based surveys. Stool samples from 232 individuals aged ≥15 years were examined by the Kato-Katz method (three samples) and a formalin ethyl-acetate concentration technique (one sample). Opisthorchis viverrini and minute intestinal flukes (MIF) were common, with prevalences of 86.2% and 62.9%, respectively. Hookworm was the predominant soil-transmitted helminth (65.9%). The prevalences of Taenia spp., Strongyloides stercoralis and Trichuris trichiura were 22.8%, 10.3% and 8.6%, respectively. Additionally, 97 individuals were purged; O. viverrini and Haplorchis taichui were found in 95 and 76 participants, respectively. Other trematodes included Phaneropsolus bonnei (22.7%), Prosthodendrium molenkampi (14.4%), Haplorchis pumilio (5.2%), Haplorchis yokogawai (3.1%) and Echinochasmus japonicus (3.1%). Co-infection with O. viverrini and MIFs was rampant (81.4%). Polytrematode infection is highly prevalent in Lao PDR and hence requires urgent attention.

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Section: Discussionsupporting

confidence: 53%

Section: Discussioncontrasting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

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Diversity of human intestinal helminthiasis in Lao PDR

Sayasone

Vonghajack

Vanmany

et al. 2009

Transactions of the Royal Society of Tropical Medicine and Hygi

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109

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“…The epidemiological data were derived from a cross-sectional community-based survey described in detail elsewhere (Steinmann et al, 2007). In brief, the study included 35 villages that were identified by randomly selecting cells of a 3.5 x 3.5 km-grid laid over a map of Eryuan county.…”

Section: Cross-sectional Parasitological and Questionnaire Surveysmentioning

confidence: 99%

“…It is known that the intermediate host snail of S. japonicum mainly lives in irrigation canals in Eryuan county. In addition, preceding analyses indicated that most S. japonicum infections occurred at an elevation below 2,150 m (Steinmann et al, 2007). Therefore, an attempt was made to classify the environment into plain regions (slope <5°) and sloped areas below or above 2,150 m. The underlying assumption was that irrigation is more common in plain areas when compared to mountain slopes.…”

Section: Gov/) Slopes (In Degrees [°]mentioning

confidence: 99%

Spatial risk profiling of Schistosoma japonicum in Eryuan county, Yunnan province, China

et al. 2007

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Abstract. Bayesian spatial risk profiling holds promise to enhance our understanding of the epidemiology of parasitic diseases, and to target interventions in a cost-effective manner. Here, we present findings from a study using Bayesian variogram models to map and predict the seroprevalence of Schistosoma japonicum in Eryuan county, Yunnan province, China, including risk factor analysis. Questionnaire and serological data were obtained through a cross-sectional survey carried out in 35 randomly selected villages with 3,220 people enrolled. Remotely-sensed environmental data were derived from publicly available databases. Bivariate and non-spatial Bayesian multiple logistic regression models were used to identify associations between the local seroprevalence and demographic (i.e. age and sex), environmental (i.e. location of village, altitude, slope, land surface temperature and normalized difference vegetation index) and socio-economic factors. In the spatially-explicit Bayesian model, S. japonicum seroprevalence was significantly associated with sex, age and the location of the village. Males, those aged below 10 years and inhabitants of villages situated on steep slopes (inclination ≥20°) or on less precipitous slopes of >5°above 2,150 m were at lower risk of seroconversion than their respective counterparts. Our final prediction model revealed an elevated risk for seroconversion in the plains of the eastern parts of Eryuan county. In conclusion, the prediction map can be utilized for spatial targeting of schistosomiasis control interventions in Eryuan county. Moreover, S. japonicum seroprevalence studies might offer a convenient means to assess the infection pressure experienced by local communities, and to improve risk profiling in areas where the prevalence and infection intensities have come down following repeated rounds of praziquantel administration.

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On Improving the Performance of Logistic Regression Analysis Via Extreme Ranking

Samawi

2020

Emerging Topics in Statistics and Biostatistics

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Helminth infections and risk factor analysis among residents in Eryuan county, Yunnan province, China

Cited by 70 publications

References 29 publications

Diversity of human intestinal helminthiasis in Lao PDR

Diversity of human intestinal helminthiasis in Lao PDR

Spatial risk profiling of Schistosoma japonicum in Eryuan county, Yunnan province, China

On Improving the Performance of Logistic Regression Analysis Via Extreme Ranking

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