HELLP syndrome: utility of specific classifications as prognostic tools

Souissi, R; Haddad, Z; Trabelsi, W.; Baffoun, N.; Boubaker, Moncef; Kaddour, C; Skandrani, L

doi:10.1186/cc5543

Cited by 1 publication

(2 citation statements)

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“…Previous studies have demonstrated that eclampsia [ 15 ], HELLP syndrome [ 16 ], twin pregnancy [ 17 ] with fetal distress [ 8 ] during childbirth, PPROM, spontaneous preterm delivery, and iatrogenic preterm delivery [ 18 ] are associated with NICU admission. Similarly, we found that these factors, along with the type of prenatal screening, are independent predictors of NICU admission for infants born to mothers of AMA.…”

Section: Discussionmentioning

confidence: 99%

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Development and validation of a prenatal predictive nomogram for the risk of NICU admission in infants born to Chinese mothers over 35 years of age: a retrospective cohort study

Wei,

Xu,

Sun

et al. 2024

BMC Pregnancy Childbirth

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Background The rising number of women giving birth at advanced maternal age has posed significant challenges in obstetric care in recent years, resulting in increased incidence of neonatal transfer to the Neonatal Intensive Care Unit (NICU). Therefore, identifying fetuses requiring NICU transfer before delivery is essential for guiding targeted preventive measures. Objective This study aims to construct and validate a nomogram for predicting the prenatal risk of NICU admission in neonates born to mothers over 35 years of age. Study design Clinical data of 4218 mothers aged ≥ 35 years who gave birth at the Department of Obstetrics of the Second Hospital of Shandong University between January 1, 2017 and December 31, 2021 were reviewed. Independent predictors were identified by multivariable logistic regression, and a predictive nomogram was subsequently constructed for the risk of neonatal NICU admission. Results Multivariate logistic regression demonstrated that the method of prenatal screening, number of implanted embryos, preterm premature rupture of the membranes, preeclampsia, HELLP syndrome, fetal distress, premature birth, and cause of preterm birth are independent predictors of neonatal NICU admission. Analysis of the nomogram decision curve based on these 8 independent predictors showed that the prediction model has good net benefit and clinical utility. Conclusion The nomogram demonstrates favorable performance in predicting the risk of neonatal NICU transfer after delivery by mothers older than 35 years. The model serves as an accurate and effective tool for clinicians to predict NICU admission in a timely manner.

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Section: Discussionmentioning

confidence: 99%

“…HELLP syndrome is a complicated form of severe PE associated with increased risks of maternal and neonatal morbidity and mortality. HELLP syndrome can be definitively cured simply by childbirth [ 16 ]. Fetal distress is a widely recognized cause of adverse neonatal outcomes.…”

Section: Discussionmentioning

confidence: 99%